Anti-PPM1G Antibody (CAB12173)
- SKU:
- CAB12173
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-PPM1G Antibody |
| 抗体コード: | CAB12173 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-546 of human PPM1G (NP_817092.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | A-431, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-546 of human PPM1G (NP_817092.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DTEE AEED DEEE EEEM MVPG MEGK EEPG SDSG TTAV VALI RGKQ LIVA NAGD SRCV VSEA GKAL DMSY DHKP EDEV ELAR IKNA GGKV TMDG RVNG GLNL SRAI GDHF YKRN KNLP PEEQ MISA LPDI KVLT LTDD HEFM VIAC DGIW NVMS SQEV VDFI QSKI SQRD ENGE LRLL SSIV EELL DQCL APDT SGDG TGCD NMTC IIIC FKPR NTAE LQPE SGKR KLEE VLST EGAE ENGN SDKK KKAK RD |
| 遺伝子ID: | 5496 |
| Uniprot: | O15355 |
| セルラーロケーション: | Cytoplasm, Lipid-anchor, Membrane |
| 計算された分子量: | 59kDa |
| 観察された分子量: | 75kDa |
| 同義語: | PPM1G, PP2CG, PP2CGAMMA, PPP2CG |
| バックグラウンド: | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. |
| UniProt Protein Function: | PPM1G: is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010] |
| UniProt Protein Details: | Protein type:Spliceosome; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: nucleoplasm; cytoplasm; nucleus Molecular Function:protein binding; metal ion binding; protein serine/threonine phosphatase activity Biological Process: protein amino acid dephosphorylation; cell cycle arrest |
| NCBI Summary: | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010] |
| UniProt Code: | O15355 |
| NCBI GenInfo Identifier: | 3122589 |
| NCBI Gene ID: | 5496 |
| NCBI Accession: | O15355.1 |
| UniProt Related Accession: | O15355 |
| Molecular Weight: | |
| NCBI Full Name: | Protein phosphatase 1G |
| NCBI Synonym Full Names: | protein phosphatase, Mg2+/Mn2+ dependent 1G |
| NCBI Official Symbol: | PPM1G |
| NCBI Official Synonym Symbols: | PP2CG; PPP2CG; PP2CGAMMA |
| NCBI Protein Information: | protein phosphatase 1G |
| UniProt Protein Name: | Protein phosphatase 1G |
| UniProt Synonym Protein Names: | Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma |
| Protein Family: | Protein phosphatase |
| UniProt Gene Name: | PPM1G |
| UniProt Entry Name: | PPM1G_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPM1G antibody (CAB12173) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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