Anti-PPIF Antibody (CAB3208)
- SKU:
- CAB3208
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | Anti-PPIF Antibody |
| 抗体コード: | CAB3208 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human PPIF (NP_005720.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HepG2, B cells, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human PPIF (NP_005720.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CSKG SGDP SSSS SSGN PLVY LDVD ANGK PLGR VVLE LKAD VVPK TAEN FRAL CTGE KGFG YKGS TFHR VIPS FMCQ AGDF TNHN GTGG KSIY GSRF PDEN FTLK HVGP GVLS MANA GPNT NGSQ FFIC TIKT DWLD GKHV VFGH VKEG MDVV KKIE SFGS KSGR TSKK IVIT DCGQ LS |
| 遺伝子ID: | 10105 |
| Uniprot: | P30405 |
| セルラーロケーション: | Mitochondrion matrix |
| 計算された分子量: | 16kDa/22kDa |
| 観察された分子量: | 18kDa |
| 同義語: | PPIF, CYP3, CyP-M, Cyp-D, CypD |
| バックグラウンド: | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. |
| UniProt Protein Function: | PPIF: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. |
| UniProt Protein Details: | Protein type:EC 5.2.1.8; Isomerase; Mitochondrial Chromosomal Location of Human Ortholog: 10q22.3 Cellular Component: membrane; mitochondrial matrix; mitochondrial proton-transporting ATP synthase complex Molecular Function:peptidyl-prolyl cis-trans isomerase activity; protein binding Biological Process: negative regulation of apoptosis; negative regulation of ATPase activity; regulation of mitochondrial membrane permeability |
| NCBI Summary: | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30405 |
| NCBI GenInfo Identifier: | 231968 |
| NCBI Gene ID: | 10105 |
| NCBI Accession: | P30405.1 |
| UniProt Secondary Accession: | P30405,Q2YDB7, Q5W131, |
| UniProt Related Accession: | P30405 |
| Molecular Weight: | 16,541 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial |
| NCBI Synonym Full Names: | peptidylprolyl isomerase F |
| NCBI Official Symbol: | PPIF |
| NCBI Official Synonym Symbols: | CYP3; CypD; CyP-M; Cyp-D |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase F, mitochondrial |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase F, mitochondrial |
| UniProt Synonym Protein Names: | Cyclophilin D; CyP-D; CypD; Cyclophilin F; Mitochondrial cyclophilin; CyP-M; Rotamase F |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIF |
| UniProt Entry Name: | PPIF_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPIF antibody (CAB3208) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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