Anti-POLL Antibody (CAB8408)
- SKU:
- CAB8408
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-POLL Antibody |
| 抗体コード: | CAB8408 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-575 of human POLL (NP_037406.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, HL-60, A-549, NCI-H460, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 421-575 of human POLL (NP_037406.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GKAT CGDV DVLI THPD GRSH RGIF SRLL DSLR QEGF LTDD LVSQ EENG QQQK YLGV CRLP GPGR RHRR LDII VVPY SEFA CALL YFTG SAHF NRSM RALA KTKG MSLS EHAL STAV VRNT HGCK VGPG RVLP TPTE KDVF RLLG LPYR EPAE RDW |
| 遺伝子ID: | 27343 |
| Uniprot: | Q9UGP5 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 33kDa/63kDa |
| 観察された分子量: | 63kDa |
| 同義語: | POLL, BETAN, POLKAPPA |
| バックグラウンド: | This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | POLL: Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. Belongs to the DNA polymerase type-X family. |
| UniProt Protein Details: | Protein type:EC 2.7.7.7; DNA repair, damage; Transferase; Lyase Chromosomal Location of Human Ortholog: 10q23 Cellular Component: nucleoplasm Molecular Function:DNA-directed DNA polymerase activity Biological Process: double-strand break repair via nonhomologous end joining; nucleotide-excision repair |
| NCBI Summary: | This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9UGP5 |
| NCBI GenInfo Identifier: | 17367126 |
| NCBI Gene ID: | 27343 |
| NCBI Accession: | Q9UGP5.1 |
| UniProt Secondary Accession: | Q9UGP5,Q5JQP5, Q6NUM2, Q9BTN8, Q9HA10, Q9HB35, D3DR76 |
| UniProt Related Accession: | Q9UGP5 |
| Molecular Weight: | 33,839 Da |
| NCBI Full Name: | DNA polymerase lambda |
| NCBI Synonym Full Names: | polymerase (DNA) lambda |
| NCBI Official Symbol: | POLL |
| NCBI Official Synonym Symbols: | BETAN; POLKAPPA |
| NCBI Protein Information: | DNA polymerase lambda |
| UniProt Protein Name: | DNA polymerase lambda |
| UniProt Synonym Protein Names: | DNA polymerase beta-2; Pol beta2; DNA polymerase kappa |
| Protein Family: | Pollen allergen |
| UniProt Gene Name: | POLL |
| UniProt Entry Name: | DPOLL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using POLL antibody (CAB8408) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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