Anti-PCYT1A Antibody (RACO0560)
- SKU:
- RACO0560
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- IF
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | PCYT1A Antibody |
| Product SKU: | RACO0560 |
| サイズ: | 50ul |
| 宿主種: | Homo sapiens (Human) |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | WB:1:500-1:5000, IF:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human PCYT1A |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Controls phosphatidylcholine synthesis. |
| シノニム: | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A), PCYT1A, CTPCT PCYT1 |
 | Immunofluorescence staining of Hela Cells with RACO0560 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
 | Western Blot. Positive WB detected in K562 whole cell lysate All lanes PCYT1A antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 42 kDa. Observed band size: 42 kDa. |
| UniProt Protein Function: | PCYT1A: Controls phosphatidylcholine synthesis. Homodimer. By phosphorylation. Belongs to the cytidylyltransferase family. |
| UniProt Protein Details: | Protein type:Transferase; Lipid Metabolism - glycerophospholipid; EC 2.7.7.15 Chromosomal Location of Human Ortholog: 3q29 Cellular Component: endoplasmic reticulum membrane; glycogen granule Molecular Function:choline-phosphate cytidylyltransferase activity Biological Process: CDP-choline pathway; phosphatidylcholine biosynthetic process Disease: Spondylometaphyseal Dysplasia With Cone-rod Dystrophy |
| NCBI Summary: | This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P49585 |
| NCBI GenInfo Identifier: | 166214967 |
| NCBI Gene ID: | 5130 |
| NCBI Accession: | P49585.2 |
| UniProt Secondary Accession: | P49585,Q86Y88, A9LYK9, D3DXB1, |
| UniProt Related Accession: | P49585 |
| Molecular Weight: | 41,731 Da |
| NCBI Full Name: | Choline-phosphate cytidylyltransferase A |
| NCBI Synonym Full Names: | phosphate cytidylyltransferase 1, choline, alpha |
| NCBI Official Symbol: | PCYT1A |
| NCBI Official Synonym Symbols: | CT; CTA; CCTA; CTPCT; PCYT1; SMDCRD |
| NCBI Protein Information: | choline-phosphate cytidylyltransferase A |
| UniProt Protein Name: | Choline-phosphate cytidylyltransferase A |
| UniProt Synonym Protein Names: | CCT-alpha; CTP:phosphocholine cytidylyltransferase A; CCT A; CT A; Phosphorylcholine transferase A |
| Protein Family: | Choline-phosphate cytidylyltransferase |
| UniProt Gene Name: | PCYT1A |
| UniProt Entry Name: | PCY1A_HUMAN |