Anti-OTUD7B Antibody (CAB17329)
- SKU:
- CAB17329
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-OTUD7B Antibody |
| 抗体コード: | CAB17329 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 530-700 of human OTUD7B (NP_064590.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | mouse liver, mouse kidney, mouse brain, rat liver, rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 530-700 of human OTUD7B (NP_064590.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SKPG GVGT GLGG SSGT ETLE KKKK NSLK SWKG GKEE AAGD GPVS EKPP AESV GNGG SKYS QEVM QSLS ILRT AMQG EGKF IFVG TLKM GHRH QYQE EMIQ RYLS DAEE RFLA EQKQ KEAE RKIM NGGI GGGP PPAK KPEP DARE EQPT GPPA ESRA MAFS TGYP GDFT IPR |
| 遺伝子ID: | 56957 |
| Uniprot: | Q6GQQ9 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 88kDa/92kDa |
| 観察された分子量: | 95Da |
| 同義語: | OTUD7B, CEZANNE, ZA20D1 |
| バックグラウンド: |
| UniProt Protein Function: | Cezanne: cellular zinc finger anti-NF-kappaB, a negative regulator of NF-kappaB. A novel deubiquitinating enzyme that belongs to the ovarian tumor protein (OTU) superfamily. |
| UniProt Protein Details: | Protein type:EC 3.4.19.12; Ubiquitin conjugating system; Protease Chromosomal Location of Human Ortholog: 1q21.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; DNA binding; zinc ion binding; ubiquitin-specific protease activity; cysteine-type peptidase activity Biological Process: mucosal immune response; negative regulation of interleukin-8 production; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of transcription from RNA polymerase II promoter; proteolysis |
| UniProt Code: | Q6GQQ9 |
| NCBI GenInfo Identifier: | 51701318 |
| NCBI Gene ID: | 56957 |
| NCBI Accession: | Q6GQQ9.1 |
| UniProt Related Accession: | Q6GQQ9 |
| Molecular Weight: | |
| NCBI Full Name: | OTU domain-containing protein 7B |
| NCBI Synonym Full Names: | OTU deubiquitinase 7B |
| NCBI Official Symbol: | OTUD7B |
| NCBI Official Synonym Symbols: | ZA20D1; CEZANNE |
| NCBI Protein Information: | OTU domain-containing protein 7B |
| UniProt Protein Name: | OTU domain-containing protein 7B |
| UniProt Synonym Protein Names: | Cellular zinc finger anti-NF-kappa-B protein; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne |
| UniProt Gene Name: | OTUD7B |
| UniProt Entry Name: | OTU7B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OTUD7B antibody (CAB17329) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded Human colon using OTUD7B Rabbit pAb (CAB17329) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of L929 cells using OTUD7B antibody (CAB17329) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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