Anti-OTUD6B Antibody (CAB14511)
- SKU:
- CAB14511
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-OTUD6B Antibody |
| 抗体コード: | CAB14511 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-323 of human OTUD6B (NP_057107.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, Raji, 293T, A-431, Jurkat, Mouse brain, Mouse heart, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-323 of human OTUD6B (NP_057107.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEAV LTEE LDEE EQLL RRHR KEKK ELQA KIQG MKNA VPKN DKKR RKQL TEDV AKLE KEME QKHR EELE QLKL TTKE NKID SVAV NISN LVLE NQPP RISK AQKR REKK AALE KERE ERIA EAEI ENLT GARH MESE KLAQ ILAA RQLE IKQI PSDG HCMY KAIE DQLK EKDC ALTV VALR SQTA EYMQ SHVE DFLP FLTN PNTG DMYT PEEF QKYC EDIV NTAA WGGQ LELR ALSH ILQT PIEI IQAD SPPI IVGE EYSK KPLI LVYM RHAY GLGE HYNS VTRL VNIV TENC S |
| 遺伝子ID: | 51633 |
| Uniprot: | Q8N6M0 |
| セルラーロケーション: | |
| 計算された分子量: | 21kDa/33kDa |
| 観察された分子量: | 38kDa |
| 同義語: | OTUD6B, CGI-77, DUBA-5, DUBA5, IDDFSDA |
| バックグラウンド: | This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells. |
| UniProt Protein Function: | OTUD6B: 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Protein type:Ubiquitin-specific protease; EC 3.4.19.12 Chromosomal Location of Human Ortholog: 8q21.3 |
| NCBI Summary: | This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells. [provided by RefSeq, Nov 2013] |
| UniProt Code: | Q8N6M0 |
| NCBI GenInfo Identifier: | 20987238 |
| NCBI Gene ID: | 51633 |
| NCBI Accession: | BC029760 |
| UniProt Secondary Accession: | Q8N6M0,Q9NTA4, Q9Y387, A8K6I1, B4DEY0, |
| UniProt Related Accession: | Q8N6M0 |
| Molecular Weight: | 21,809 Da |
| NCBI Full Name: | Homo sapiens OTU domain containing 6B, mRNA |
| NCBI Synonym Full Names: | OTU domain containing 6B |
| NCBI Official Symbol: | OTUD6B |
| NCBI Official Synonym Symbols: | DUBA5; CGI-77; DUBA-5 |
| NCBI Protein Information: | OTU domain-containing protein 6B |
| UniProt Protein Name: | OTU domain-containing protein 6B |
| UniProt Synonym Protein Names: | DUBA-5 |
| Protein Family: | OTU domain-containing protein |
| UniProt Gene Name: | OTUD6B |
| UniProt Entry Name: | OTU6B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OTUD6B antibody (CAB14511) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunoprecipitation analysis of 200ug extracts of U-87MG cells using 3ug OTUD6B antibody (CAB14511). Western blot was performed from the immunoprecipitate using OTUD6B antibody (CAB14511) at a dilition of 1:1000. |
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