Anti-NUP133 Antibody (CAB8818)
- SKU:
- CAB8818
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-NUP133 Antibody |
| 抗体コード: | CAB8818 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-930 of human NUP133 (NP_060700.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | A375, LO2, HeLa, NCI-H460 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 730-930 of human NUP133 (NP_060700.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | NILK DMLQ AASH YRQN RNSL YRRE ESLE KEPE YVPW TATS GPGG IRTV IIRQ HEIV LKVA YPQA DSNL RNIV TEQL VALI DCFL DGYV SQLK SVDK SSNR ERYD NLEM EYLQ KRSD LLSP LLSL GQYL WAAS LAEK YCDF DILV QMCE QTDN QSRL QRYM TQFA DQNF SDFL FRWY LEKG KRGK LLSQ PISQ HGQL ANFL Q |
| 遺伝子ID: | 55746 |
| Uniprot: | Q8WUM0 |
| セルラーロケーション: | Chromosome, Nucleus, centromere, kinetochore, nuclear pore complex |
| 計算された分子量: | 128kDa |
| 観察された分子量: | 133kDa |
| 同義語: | NUP133, hNUP133 |
| バックグラウンド: | The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. |
| NCBI Summary: | The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WUM0 |
| NCBI GenInfo Identifier: | 26051235 |
| NCBI Gene ID: | 55746 |
| NCBI Accession: | NP_060700.2 |
| UniProt Related Accession: | Q8WUM0 |
| Molecular Weight: | |
| NCBI Full Name: | nuclear pore complex protein Nup133 |
| NCBI Synonym Full Names: | nucleoporin 133 |
| NCBI Official Symbol: | NUP133 |
| NCBI Official Synonym Symbols: | GAMOS8; NPHS18; hNUP133 |
| NCBI Protein Information: | nuclear pore complex protein Nup133 |
| UniProt Protein Name: | Nuclear pore complex protein Nup133 |
| UniProt Synonym Protein Names: | 133 kDa nucleoporin; Nucleoporin Nup133 |
| UniProt Gene Name: | NUP133 |
| UniProt Entry Name: | NU133_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NUP133 antibody (CAB8818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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