Anti-NOP58 Antibody (CAB14129)
- SKU:
- CAB14129
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-NOP58 Antibody |
| 抗体コード: | CAB14129 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-529 of human NOP58 (NP_057018.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A375, HeLa, SH-SY5Y, K-562, Jurkat, HepG2, Mouse liver, Mouse brain, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-529 of human NOP58 (NP_057018.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RMLA AKTV LAIR YDAF GEDS SSAM GVEN RAKL EARL RTLE DRGI RKIS GTGK ALAK TEKY EHKS EVKT YDPS GDST LPTC SKKR KIEQ VDKE DEIT EKKA KKAK IKVK VEEE EEEK VAEE EETS VKKK KKRG KKKH IKEE PLSE EEPC TSTA IASP EKKK KKKK KREN ED |
| 遺伝子ID: | 51602 |
| Uniprot: | Q9Y2X3 |
| セルラーロケーション: | Nucleus, nucleolus, nucleoplasm |
| 計算された分子量: | 59kDa |
| 観察された分子量: | 68kDa |
| 同義語: | NOP58, HSPC120, NOP5, NOP5/NOP58 |
| バックグラウンド: | The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs. |
| UniProt Protein Function: | NOP5: Required for 60S ribosomal subunit biogenesis. Belongs to the NOP5/NOP56 family. |
| UniProt Protein Details: | Protein type:Nucleolus; Cell development/differentiation; RNA-binding Chromosomal Location of Human Ortholog: 2q33.1 Cellular Component: Cajal body; small nucleolar ribonucleoprotein complex; membrane; cytoplasm; nucleolus; nucleus Molecular Function:snoRNA binding; protein binding Biological Process: rRNA modification; snRNP protein import into nucleus; cell growth; rRNA processing |
| UniProt Code: | Q9Y2X3 |
| NCBI GenInfo Identifier: | 17380155 |
| NCBI Gene ID: | 51602 |
| NCBI Accession: | Q9Y2X3.1 |
| UniProt Secondary Accession: | Q9Y2X3,Q53SA4, Q6PK08, Q9P036, Q9UFN3, |
| UniProt Related Accession: | Q9Y2X3 |
| Molecular Weight: | 529 |
| NCBI Full Name: | Nucleolar protein 58 |
| NCBI Synonym Full Names: | NOP58 ribonucleoprotein |
| NCBI Official Symbol: | NOP58 |
| NCBI Official Synonym Symbols: | NOP5; HSPC120; NOP5/NOP58 |
| NCBI Protein Information: | nucleolar protein 58; nucleolar protein NOP5/NOP58; NOP58 ribonucleoprotein homolog |
| UniProt Protein Name: | Nucleolar protein 58 |
| UniProt Synonym Protein Names: | Nucleolar protein 5 |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP58 |
| UniProt Entry Name: | NOP58_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NOP58 antibody (CAB14129) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Confocal immunofluorescence analysis of U2OS cells using NOP58 Polyclonal Antibody (CAB14129) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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