Anti-NLRC5 Antibody (CAB16740)
- SKU:
- CAB16740
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-NLRC5 Antibody |
| 抗体コード: | CAB16740 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human NLRC5 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | mouse lung |
| 免疫原: | Recombinant protein of human NLRC5 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 84166 |
| Uniprot: | Q86WI3 |
| セルラーロケーション: | |
| 計算された分子量: | 204kDa |
| 観察された分子量: | 204kDa |
| 同義語: | NLRC5, CLR16.1, NOD27, NOD4 |
| バックグラウンド: | This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. |
| UniProt Protein Function: | NLRC5: Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. Belongs to the NLRP family. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16q13 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:protein binding; ATP binding Biological Process: regulation of kinase activity; inhibition of NF-kappaB transcription factor; innate immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of MHC class I biosynthetic process; defense response to virus; negative regulation of interferon type I production |
| NCBI Summary: | This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q86WI3 |
| NCBI GenInfo Identifier: | 350529351 |
| NCBI Gene ID: | 84166 |
| NCBI Accession: | NP_115582 |
| UniProt Secondary Accession: | Q86WI3,Q6P4A6, Q86VM7, Q8NF42, Q8TEE2, Q8TEJ1, Q969L7 B5MEF1, C9JMD8, |
| UniProt Related Accession: | Q86WI3 |
| Molecular Weight: | 170,417 Da |
| NCBI Full Name: | protein NLRC5 |
| NCBI Synonym Full Names: | NLR family, CARD domain containing 5 |
| NCBI Official Symbol: | NLRC5 |
| NCBI Official Synonym Symbols: | NOD4; NOD27; CLR16.1 |
| NCBI Protein Information: | protein NLRC5 |
| UniProt Protein Name: | Protein NLRC5 |
| UniProt Synonym Protein Names: | Caterpiller protein 16.1; CLR16.1; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4 |
| UniProt Gene Name: | NLRC5 |
| UniProt Entry Name: | NLRC5_HUMAN |
 | Western blot analysis of extracts of mouse lung, using NLRC5 antibody (CAB16740) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 3min. |
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