Anti-NKD1 Antibody (CAB17799)
- SKU:
- CAB17799
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-NKD1 Antibody |
| 抗体コード: | CAB17799 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of Human NKD1. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | 293T, LO2 |
| 免疫原: | A synthetic peptide of Human NKD1. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 85407 |
| Uniprot: | Q969G9 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 60kDa |
 | Western blot - NKD1 Polyclonal Antibody (CAB17799) |
| 同義語: | Naked1, NKD1 |
| バックグラウンド: | In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003] |
| UniProt Protein Function: | NKD1: Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Interacts with DVL1, DVL2, DVL3 and PPP2R3A. Expression is induced by activation of the Wnt signaling pathway. Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen. Belongs to the NKD family. |
| UniProt Protein Details: | Protein type:Cell development/differentiation Chromosomal Location of Human Ortholog: 16q12.1 Cellular Component: cytoplasm; protein phosphatase type 2A complex Molecular Function:protein binding Biological Process: eye photoreceptor cell differentiation; positive regulation of protein catabolic process; somatic muscle development |
| NCBI Summary: | In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.[supplied by OMIM, Jun 2003] |
| UniProt Code: | Q969G9 |
| NCBI GenInfo Identifier: | 74731040 |
| NCBI Gene ID: | 85407 |
| NCBI Accession: | Q969G9.1 |
| UniProt Secondary Accession: | Q969G9,Q8WZ08, B2RC39, |
| UniProt Related Accession: | Q969G9 |
| Molecular Weight: | 52,285 Da |
| NCBI Full Name: | Protein naked cuticle homolog 1 |
| NCBI Synonym Full Names: | naked cuticle homolog 1 |
| NCBI Official Symbol: | NKD1 |
| NCBI Official Synonym Symbols: | Naked1 |
| NCBI Protein Information: | protein naked cuticle homolog 1 |
| UniProt Protein Name: | Protein naked cuticle homolog 1 |
| Protein Family: | Protein naked cuticle |
| UniProt Gene Name: | NKD1 |
| UniProt Entry Name: | NKD1_HUMAN |