UniProt Protein Function: | May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play a role in the control of tumor development and progression; restored MYO18B expression in lung cancer cells suppresses anchorage-independent growth. |
NCBI Summary: | The protein encoded by this gene may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IUG5 |
NCBI GenInfo Identifier: | 970949420 |
NCBI Gene ID: | 84700 |
NCBI Accession: | NP_001305174.1 |
UniProt Secondary Accession: | Q8IUG5,Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9 A0A075B6F5, B2RWP3, F5GXR6, F5GYU7, |
UniProt Related Accession: | Q8IUG5 |
Molecular Weight: | 282 |
NCBI Full Name: | unconventional myosin-XVIIIb isoform 1 |
NCBI Synonym Full Names: | myosin XVIIIB |
NCBI Official Symbol: | MYO18B |
NCBI Official Synonym Symbols: | KFS4 |
NCBI Protein Information: | unconventional myosin-XVIIIb |
UniProt Protein Name: | Unconventional myosin-XVIIIb |
UniProt Gene Name: | MYO18B |