Anti-MYL9 Antibody (CAB3039)
- SKU:
- CAB3039
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MYL9 Antibody |
| 抗体コード: | CAB3039 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYL9 (NP_006088.2). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse lung, Mouse testis, Rat uterus |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYL9 (NP_006088.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSSK RAKA KTTK KRPQ RATS NVFA MFDQ SQIQ EFKE AFNM IDQN RDGF IDKE DLHD MLAS LGKN PTDE YLEG MMSE APGP INFT MFLT MFGE KLNG TDPE |
| 遺伝子ID: | 10398 |
| Uniprot: | P24844 |
| セルラーロケーション: | |
| 計算された分子量: | 13kDa/19kDa |
| 観察された分子量: | 20kDa |
| 同義語: | MYL9, LC20, MLC-2C, MLC2, MRLC1, MYRL2 |
| バックグラウンド: | Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | MRLC1: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains. Smooth muscle tissues and in some, but not all, nonmuscle cells. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Contractile; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q11.23 Cellular Component: cytosol; muscle myosin complex; stress fiber; Z disc Molecular Function:calcium ion binding; myosin heavy chain binding; structural constituent of muscle Biological Process: axon guidance; ephrin receptor signaling pathway; muscle contraction; regulation of muscle contraction; small GTPase mediated signal transduction |
| NCBI Summary: | Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P24844 |
| NCBI GenInfo Identifier: | 20141521 |
| NCBI Gene ID: | 10398 |
| NCBI Accession: | P24844.4 |
| UniProt Secondary Accession: | P24844,Q9BQL9, Q9BUF9, Q9H136, E1P5T6, |
| UniProt Related Accession: | P24844 |
| Molecular Weight: | 13,866 Da |
| NCBI Full Name: | Myosin regulatory light polypeptide 9 |
| NCBI Synonym Full Names: | myosin light chain 9 |
| NCBI Official Symbol: | MYL9 |
| NCBI Official Synonym Symbols: | LC20; MLC2; MRLC1; MYRL2; MLC-2C |
| NCBI Protein Information: | myosin regulatory light polypeptide 9 |
| UniProt Protein Name: | Myosin regulatory light polypeptide 9 |
| UniProt Synonym Protein Names: | 20 kDa myosin light chain; LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1 |
| Protein Family: | Myosin regulatory light polypeptide |
| UniProt Gene Name: | MYL9 |
| UniProt Entry Name: | MYL9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MYL9 antibody (CAB3039) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of Rat intestine using MYL9 antibody (CAB3039) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of Human colon carcinoma using MYL9 antibody (CAB3039) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of Mouse intestine using MYL9 antibody (CAB3039) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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