Anti-MTCH1 Antibody (CAB8063)
- SKU:
- CAB8063
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | MTCH1 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8063 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human MTCH1 (NP_001258570.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, HepG2, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human MTCH1 (NP_001258570.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LYVK LLIQ VGHE PMPP TLGT NVLG RKVL YLPS FFTY AKYI VQVD GKIG LFRG LSPR LMSN ALST VTRG SMKK VFPP DEIE QVSN KDDM KTSL KKVV KETS YEMM MQCV SRML AHPL HVIS MRCM VQFV GREA KYSG VLSS IGKI FKEE GLL |
| 遺伝子ID: | 23787 |
| Uniprot: | Q9NZJ7 |
| セルラーロケーション: | Mitochondrion inner membrane, Multi-pass membrane protein |
| 計算された分子量: | 19kDa/39kDa/41kDa |
| 観察された分子量: | 45-50kDa |
| 同義語: | MTCH1, CGI-64, PIG60, PSAP, SLC25A49 |
| バックグラウンド: | This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. |
| UniProt Protein Function: | MTCH1: Potential mitochondrial transporter. May play a role in apoptosis. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial Chromosomal Location of Human Ortholog: 6p21.2 Cellular Component: membrane; mitochondrion Molecular Function:protein binding Biological Process: caspase activation; positive regulation of apoptosis |
| NCBI Summary: | This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012] |
| UniProt Code: | Q9NZJ7 |
| NCBI GenInfo Identifier: | 74753085 |
| NCBI Gene ID: | 23787 |
| NCBI Accession: | Q9NZJ7.1 |
| UniProt Secondary Accession: | Q9NZJ7,Q6PK60, Q6UX45, Q7L465, Q9BW23, Q9NZR6, Q9UJZ5 A8KAX5, B2RCE3, |
| UniProt Related Accession: | Q9NZJ7 |
| Molecular Weight: | 19,058 Da |
| NCBI Full Name: | Mitochondrial carrier homolog 1 |
| NCBI Synonym Full Names: | mitochondrial carrier 1 |
| NCBI Official Symbol: | MTCH1 |
| NCBI Official Synonym Symbols: | PSAP; PIG60; CGI-64; SLC25A49 |
| NCBI Protein Information: | mitochondrial carrier homolog 1 |
| UniProt Protein Name: | Mitochondrial carrier homolog 1 |
| UniProt Synonym Protein Names: | Presenilin-associated protein |
| Protein Family: | Mitochondrial carrier |
| UniProt Gene Name: | MTCH1 |
| UniProt Entry Name: | MTCH1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MTCH1 antibody (CAB8063) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using MTCH1 antibody (CAB8063) at dilution of 1:100 (40x lens). |
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