Anti-MRPS6 Antibody (CAB9884)
- SKU:
- CAB9884
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MRPS6 Antibody |
| 抗体コード: | CAB9884 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human MRPS6 (NP_115865.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | B cells, MCF7, 22Rv1, Jurkat, Mouse kidney, Mouse heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human MRPS6 (NP_115865.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MPRY ELAL ILKA MQRP ETAA TLKR TIEA LMDR GAIV RDLE NLGE RALP YRIS AHSQ QHNR GGYF LVDF YAPT AAVE SMVE HLSR DIDV IRGN IVKH PLTQ ELKE CEGI VPVP LAEK LYST KKRK K |
| 遺伝子ID: | 64968 |
| Uniprot: | P82932 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 14kDa |
| 観察された分子量: | 14kDa |
| 同義語: | MRPS6, C21orf101, MRP-S6, RPMS6, S6mt |
| バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. |
| UniProt Protein Function: | MRPS6: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 21q22.11 Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit Molecular Function:protein binding; structural constituent of ribosome Biological Process: mitochondrial translation |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P82932 |
| NCBI GenInfo Identifier: | 16554616 |
| NCBI Gene ID: | 64968 |
| NCBI Accession: | NP_115865.1 |
| UniProt Secondary Accession: | P82932,Q96Q64, Q9BSK8, Q9BW89, B2R573, |
| UniProt Related Accession: | P82932 |
| Molecular Weight: | 14,227 Da |
| NCBI Full Name: | 28S ribosomal protein S6, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S6 |
| NCBI Official Symbol: | MRPS6 |
| NCBI Official Synonym Symbols: | S6mt; RPMS6; MRP-S6; C21orf101 |
| NCBI Protein Information: | 28S ribosomal protein S6, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S6, mitochondrial |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS6 |
| UniProt Entry Name: | RT06_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MRPS6 antibody (CAB9884) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunohistochemistry of paraffin-embedded mouse heart using MRPS6 antibody (CAB9884) at dilution of 1:100 (40x lens). |
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