Anti-MRPL51 Antibody (CAB15838)
- SKU:
- CAB15838
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-MRPL51 Antibody |
| 抗体コード: | CAB15838 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL51 (NP_057581.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Rat heart, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL51 (NP_057581.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAGN LLSG AGRR LWDW VPLA CRSF SLGV PRLI GIRL TLPP PKVV DRWN EKRA MFGV YDNI GILG NFEK HPKE LIRG PIWL RGWK GNEL QRCI RKRK MVGS RMFA DDLH NLNK RIRY LYKH FNRH GKFR |
| 遺伝子ID: | 51258 |
| Uniprot: | Q4U2R6 |
| セルラーロケーション: | Mitochondrion |
| 計算された分子量: | 15kDa |
| 観察された分子量: | 14kDa |
| 同義語: | MRPL51, CDA09, HSPC241, MRP64, bMRP64 |
| バックグラウンド: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. |
| UniProt Protein Function: | MRPL51: Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins. |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 12p13.3-p13.1 Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrial ribosome Molecular Function:protein binding; structural constituent of ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis; translation |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q4U2R6 |
| NCBI GenInfo Identifier: | 74762954 |
| NCBI Gene ID: | 51258 |
| NCBI Accession: | Q4U2R6.1 |
| UniProt Secondary Accession: | Q4U2R6,Q96Q57, Q9BQ36, Q9P0N7, |
| UniProt Related Accession: | Q4U2R6 |
| Molecular Weight: | 15,095 Da |
| NCBI Full Name: | 39S ribosomal protein L51, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L51 |
| NCBI Official Symbol: | MRPL51 |
| NCBI Official Synonym Symbols: | CDA09; MRP64; bMRP64; HSPC241 |
| NCBI Protein Information: | 39S ribosomal protein L51, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L51, mitochondrial |
| UniProt Synonym Protein Names: | bMRP-64; bMRP64 |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL51 |
| UniProt Entry Name: | RM51_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MRPL51 antibody (CAB15838) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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