Anti-MPP1 Antibody (CAB6298)
- SKU:
- CAB6298
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MPP1 Antibody |
抗体コード: | CAB6298 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MPP1 (NP_002427.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | 293T, Mouse kidney, Mouse thymus |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MPP1 (NP_002427.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MTLK ASEG ESGG SMHT ALSD LYLE HLLQ KRSR PEAV SHPL NTVT EDMY TNGS PAPG SPAQ VKGQ EVRK VRLI QFEK VTEE PMGI TLKL NEKQ SCTV ARIL HGGM IHRQ GSLH VGDE ILEI NGTN VTNH SVDQ LQKA MKET KGMI SLKV IPNQ QSRL PALQ MFMR AQFD YDPK KDNL IPCK EAGL KFAT GDII QIIN KDDS NWWQ GRVE GSSK ESAG LIPS PELQ EWRV ASMA QSAP SEAP SCSP FGKK KKYK DKYL AKHS SIFD QLDV VS |
遺伝子ID: | 4354 |
Uniprot: | Q00013 |
セルラーロケーション: | Cell projection, Lipid-anchor, Membrane, stereocilium |
計算された分子量: | 49kDa/52kDa |
観察された分子量: | 52kDa |
同義語: | MPP1, AAG12, DXS552E, EMP55, MRG1, PEMP |
バックグラウンド: | This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity. |
NCBI Summary: | This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q00013 |
NCBI GenInfo Identifier: | 1346575 |
NCBI Gene ID: | 4354 |
NCBI Accession: | Q00013.2 |
UniProt Secondary Accession: | Q00013,Q2TSB6, Q5J7V5, B4DZV5, G3XAI1, |
UniProt Related Accession: | Q00013 |
Molecular Weight: | 49,854 Da |
NCBI Full Name: | 55 kDa erythrocyte membrane protein |
NCBI Synonym Full Names: | membrane palmitoylated protein 1 |
NCBI Official Symbol: | MPP1 |
NCBI Official Synonym Symbols: | MRG1; PEMP; AAG12; EMP55; DXS552E |
NCBI Protein Information: | 55 kDa erythrocyte membrane protein |
UniProt Protein Name: | 55 kDa erythrocyte membrane protein |
UniProt Synonym Protein Names: | Membrane protein, palmitoylated 1 |
Protein Family: | Mitochondrial-processing peptidase |
UniProt Gene Name: | MPP1 |
UniProt Entry Name: | EM55_HUMAN |
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