UniProt Protein Function: | MLXIP: Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12q24.31 Cellular Component: nucleus Molecular Function:transcription factor activity |
NCBI Summary: | This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014] |
UniProt Code: | Q9HAP2 |
NCBI GenInfo Identifier: | 111955326 |
NCBI Gene ID: | 22877 |
NCBI Accession: | NP_055753 |
UniProt Related Accession: | Q9HAP2 |
Molecular Weight: | 101kDa |
NCBI Full Name: | MLX-interacting protein |
NCBI Synonym Full Names: | MLX interacting protein |
NCBI Official Symbol: | MLXIP |
NCBI Official Synonym Symbols: | MIR; MONDOA; bHLHe36 |
NCBI Protein Information: | MLX-interacting protein |
UniProt Protein Name: | MLX-interacting protein |
UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 36; bHLHe36; Transcriptional activator MondoA |
Protein Family: | MLX-interacting protein |
UniProt Gene Name: | MLXIP |