Anti-MFF Antibody (CAB12392)
- SKU:
- CAB12392
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-MFF Antibody |
| 抗体コード: | CAB12392 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-170 of human MFF (NP_064579.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 15-170 of human MFF (NP_064579.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SRAA FPSP TAAE MAEI SRIQ YEME YTEG ISQR MRVP EKLK VAPP NADL EQGF QEGV PNAS VIMQ VPER IVVA GNNE DVSF SRPA DLDL IQST PFKP LALK TPPR VLTL SERP LDFL DLER PPTT PQNE EIRA VGRL KRER SMSE NAVR QNGQ LVRN |
| 遺伝子ID: | 56947 |
| Uniprot: | Q9GZY8 |
| セルラーロケーション: | Cytoplasmic vesicle, Mitochondrion outer membrane, Peroxisome, Single-pass type IV membrane protein, secretory vesicle, synaptic vesicle |
| 計算された分子量: | 25kDa/27kDa/32kDa/38kDa |
| 観察された分子量: | 38kDa |
| 同義語: | MFF, C2orf33, EMPF2, GL004 |
| バックグラウンド: | This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | MFF: Plays a role in mitochondrial and peroxisomal fission. Belongs to the tango11 family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Mitochondrial Chromosomal Location of Human Ortholog: 2q36.3 Cellular Component: mitochondrial outer membrane; mitochondrion; peroxisome Molecular Function:protein binding; protein homodimerization activity Biological Process: mitochondrial fission; mitochondrial fragmentation during apoptosis; mitochondrial fusion; peroxisome fission; protein homooligomerization; protein targeting to mitochondrion; release of cytochrome c from mitochondria |
| NCBI Summary: | This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013] |
| UniProt Code: | Q9GZY8 |
| NCBI GenInfo Identifier: | 74725008 |
| NCBI Gene ID: | 56947 |
| NCBI Accession: | Q9GZY8.1 |
| UniProt Secondary Accession: | Q9GZY8,Q567U1, Q658R6, Q9BVZ1, Q9H690, Q9NRG8, |
| UniProt Related Accession: | Q9GZY8 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | Mitochondrial fission factor |
| NCBI Synonym Full Names: | mitochondrial fission factor |
| NCBI Official Symbol: | MFF |
| NCBI Official Synonym Symbols: | EMPF2; GL004; C2orf33 |
| NCBI Protein Information: | mitochondrial fission factor |
| UniProt Protein Name: | Mitochondrial fission factor |
| Protein Family: | Mitochondrial fission factor |
| UniProt Gene Name: | MFF |
 | Western blot analysis of extracts of LO2 cells, using MFF antibody (CAB12392) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
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