Anti-Methyl-U2AF1-H37 Antibody (CAB18824)
- SKU:
- CAB18824
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- U2AF1
- Synonyms:
- FP793
- Synonyms:
- RN
- Synonyms:
- RNU2AF1
- Synonyms:
- U2AF35
- Synonyms:
- U2AFBP
- Synonyms:
- splicing factor U2AF 35 kDa subunit
Frequently bought together:
Description
| 抗体名: | Methyl-U2AF1-H37 Rabbit pAb |
| 抗体コード: | CAB18824 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | U2AF1, FP793, RN, RNU2AF1, U2AF35, U2AFBP, splicing factor U2AF 35 kDa subunit |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide of human Methyl-U2AF1-H37, 3-methyl (tau-methyl). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| 免疫原: | A synthetic peptide of human Methyl-U2AF1-H37, 3-methyl (tau-methyl). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 7307 |
| Uniprot: | Q01081 |
| セルラーロケーション: | Nucleus, Nucleus speckle |
| 計算された分子量: | 8kDa/19kDa/27kDa |
| 観察された分子量: | Refer to figures |
| UniProt Protein Function: | U2AF1: Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. Belongs to the splicing factor SR family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing; RNA-binding; RNA processing Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: nucleoplasm; spliceosome; Cajal body; nuclear speck Molecular Function:RS domain binding; protein binding; metal ion binding; nucleotide binding Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3'-end processing; mRNA processing; termination of RNA polymerase II transcription |
| NCBI Summary: | This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q01081 |
| NCBI GenInfo Identifier: | 267187 |
| NCBI Gene ID: | 7307 |
| NCBI Accession: | Q01081.3 |
| UniProt Secondary Accession: | Q01081,Q701P4, Q71RF1, |
| UniProt Related Accession: | Q01081 |
| Molecular Weight: | 240 |
| NCBI Full Name: | Splicing factor U2AF 35 kDa subunit |
| NCBI Synonym Full Names: | U2 small nuclear RNA auxiliary factor 1 |
| NCBI Official Symbol: | U2AF1 |
| NCBI Official Synonym Symbols: | RN; FP793; U2AF35; U2AFBP; RNU2AF1 |
| NCBI Protein Information: | splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35kDa subunit; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit |
| UniProt Protein Name: | Splicing factor U2AF 35 kDa subunit |
| UniProt Synonym Protein Names: | U2 auxiliary factor 35 kDa subunit; U2 small nuclear RNA auxiliary factor 1; U2 snRNP auxiliary factor small subunit |
| Protein Family: | Splicing factor |
| UniProt Gene Name: | U2AF1 |
| UniProt Entry Name: | U2AF1_HUMAN |