| UniProt Protein Function: | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. |
| UniProt Code: | Q9H204 |
| NCBI GenInfo Identifier: | 52851391 |
| NCBI Gene ID: | 80306 |
| NCBI Accession: | NP_079481.2 |
| UniProt Secondary Accession: | Q9H204,Q9BZJ5, |
| UniProt Related Accession: | Q9H204 |
| Molecular Weight: | 19 |
| NCBI Full Name: | mediator of RNA polymerase II transcription subunit 28 |
| NCBI Synonym Full Names: | mediator complex subunit 28 |
| NCBI Official Symbol: | MED28 |
| NCBI Official Synonym Symbols: | EG1; magicin; 1500003D12Rik |
| NCBI Protein Information: | mediator of RNA polymerase II transcription subunit 28 |
| UniProt Protein Name: | Mediator of RNA polymerase II transcription subunit 28 |
| UniProt Synonym Protein Names: | Endothelial-derived protein 1; Mediator complex subunit 28; Merlin and Grb2-interacting cytoskeletal protein; Magicin; Tumor angiogenesis marker EG-1 |
| Protein Family: | Mediator of RNA polymerase II transcription |
| UniProt Gene Name: | MED28 |
