Anti-MATK Antibody (CAB6651)
- SKU:
- CAB6651
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-MATK Antibody |
抗体コード: | CAB6651 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | THP-1 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | PEAL KHGK FTSK SDVW SFGV LLWE VFSY GRAP YPKM SLKE VSEA VEKG YRME PPEG CPGP VHVL MSSC WEAE PARR PPFR KLAE KLAR ELRS AGAP ASVS GQDA DGST SPRS QEP |
遺伝子ID: | 4145 |
Uniprot: | P42679 |
セルラーロケーション: | Cytoplasm, Membrane |
計算された分子量: | 51kDa/56kDa |
観察された分子量: | 56kDa |
同義語: | MATK, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk |
バックグラウンド: | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. |
NCBI Summary: | The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P42679 |
NCBI GenInfo Identifier: | |
NCBI Gene ID: | 4145 |
NCBI Accession: | |
UniProt Related Accession: | P42679 |
Molecular Weight: | Observed MW: 56kDa |
NCBI Full Name: | |
NCBI Synonym Full Names: | megakaryocyte-associated tyrosine kinase |
NCBI Official Symbol: | MATK |
NCBI Official Synonym Symbols: | CHK; CTK; HYL; Lsk; HYLTK; HHYLTK |
NCBI Protein Information: | megakaryocyte-associated tyrosine-protein kinase |
UniProt Protein Name: | |
Protein Family: | Maturase |
UniProt Gene Name: |
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