Anti-MAOB Antibody (RACO0516)
- SKU:
- RACO0516
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Application:
- IHC
- Conjugation:
- Unconjugated
Description
| 商品名: | MAOB Antibody |
| Product SKU: | RACO0516 |
| サイズ: | 50ul |
| 宿主種: | Homo sapiens (Human) |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:5000, IHC:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | A synthesized peptide derived from human Monoamine Oxidase B |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. |
| シノニム: | Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B), MAOB |
 | IHC image of RACO0516 diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
 | IHC image of RACO0516 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
 | Western Blot. Positive WB detected in L02 whole cell lysate HepG2 whole cell lysate All lanes Monoamine Oxidase B Antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 59, 47 kDa. Observed band size: 59 kDa. |
| UniProt Protein Function: | MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - histidine; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tryptophan Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane Molecular Function:amine oxidase activity; protein homodimerization activity; electron carrier activity; FAD binding Biological Process: response to drug; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to selenium ion; response to ethanol; substantia nigra development; dopamine catabolic process; response to toxin; xenobiotic metabolic process; response to lipopolysaccharide; hydrogen peroxide biosynthetic process; response to corticosterone stimulus; response to aluminum ion |
| NCBI Summary: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P27338 |
| NCBI GenInfo Identifier: | 113980 |
| NCBI Gene ID: | 4129 |
| NCBI Accession: | P27338.3 |
| UniProt Secondary Accession: | P27338,Q7Z6S2, B2R6R3, B7Z5H3, D3DWC3, |
| UniProt Related Accession: | P27338 |
| Molecular Weight: | 520 |
| NCBI Full Name: | Amine oxidase |
| NCBI Synonym Full Names: | monoamine oxidase B |
| NCBI Official Symbol: | MAOB |
| NCBI Protein Information: | amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B |
| UniProt Protein Name: | Amine oxidase [flavin-containing] B |
| UniProt Synonym Protein Names: | Monoamine oxidase type B; MAO-B |
| Protein Family: | Amine oxidase |
| UniProt Gene Name: | MAOB |
| UniProt Entry Name: | AOFB_HUMAN |