Anti-LRIG1 Antibody (CAB10297)
- SKU:
- CAB10297
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LRIG1 Antibody |
| 抗体コード: | CAB10297 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-220 of human LRIG1 (NP_056356.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Raji, Mouse skin, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-220 of human LRIG1 (NP_056356.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | AGPR APCA AACT CAGD SLDC GGRG LAAL PGDL PSWT RSLN LSYN KLSE IDPA GFED LPNL QEVY LNNN ELTA VPSL GAAS SHVV SLFL QHNK IRSV EGSQ LKAY LSLE VLDL SLNN ITEV RNTC FPHG PPIK ELNL AGNR IGTL ELGA FDGL SRSL LTLR LSKN RITQ LPVR AFKL PRLT QLDL NR |
| 遺伝子ID: | 26018 |
| Uniprot: | Q96JA1 |
| セルラーロケーション: | Membrane, Single-pass type I membrane protein |
| 計算された分子量: | 116kDa/119kDa |
| 観察された分子量: | 160kDa |
| 同義語: | LRIG1, LIG-1, LIG1 |
| バックグラウンド: |
| UniProt Protein Function: | LRIG1: a singhle-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases. Regulates cadherin-dependent contact inhibition. Interacts with EGFR, HER2, -3, and -4. Two isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Protein kinase, regulatory subunit Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: plasma membrane |
| UniProt Code: | Q96JA1 |
| NCBI GenInfo Identifier: | 143811415 |
| NCBI Gene ID: | 26018 |
| NCBI Accession: | Q96JA1.2 |
| UniProt Secondary Accession: | Q96JA1,Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4, |
| UniProt Related Accession: | Q96JA1 |
| Molecular Weight: | 119kDa |
| NCBI Full Name: | Leucine-rich repeats and immunoglobulin-like domains protein 1 |
| NCBI Synonym Full Names: | leucine rich repeats and immunoglobulin like domains 1 |
| NCBI Official Symbol: | LRIG1 |
| NCBI Official Synonym Symbols: | LIG1; LIG-1 |
| NCBI Protein Information: | leucine-rich repeats and immunoglobulin-like domains protein 1 |
| UniProt Protein Name: | Leucine-rich repeats and immunoglobulin-like domains protein 1 |
| Protein Family: | Leucine-rich repeats and immunoglobulin-like domains protein |
| UniProt Gene Name: | LRIG1 |
 | Western blot analysis of extracts of various cell lines, using LRIG1 antibody (CAB10297) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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