Anti-LHX3 Antibody (CAB17015)
- SKU:
- CAB17015
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-LHX3 Antibody |
| 抗体コード: | CAB17015 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human LHX3 (NP_055379.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, SH-SY5Y, U-87MG, U-251MG, Mouse brain, Rat brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human LHX3 (NP_055379.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LEHG GLAG PEQY RELR PGSP YGVP PSPA APQS LPGP QPLL SSLV YPDT SLGL VPSG APGG PPPM RVLA GNGP SSDL STGS SGGY PDFP ASPA SWLD EVDH AQF |
| 遺伝子ID: | 8022 |
| Uniprot: | Q9UBR4 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 43kDa |
 | Western blot - LHX3 Polyclonal Antibody (CAB17015) |
| 同義語: | LHX3, CPHD3, LIM3, M2-LHX3 |
| バックグラウンド: | This gene encodes a member of a large family of proteins which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene cause combined pituitary hormone deficiency 3. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1. Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1. |
| NCBI Summary: | This gene encodes a member of a large family of proteins which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene cause combined pituitary hormone deficiency 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q9UBR4 |
| NCBI GenInfo Identifier: | 1393428460 |
| NCBI Gene ID: | 8022 |
| NCBI Accession: | NP_001350675.1 |
| UniProt Secondary Accession: | Q9UBR4,Q5TB39, Q5TB40, Q9NZB5, Q9P0I8, Q9P0I9, |
| UniProt Related Accession: | Q9UBR4 |
| Molecular Weight: | 43,978 Da |
| NCBI Full Name: | LIM/homeobox protein Lhx3 isoform c |
| NCBI Synonym Full Names: | LIM homeobox 3 |
| NCBI Official Symbol: | LHX3 |
| NCBI Official Synonym Symbols: | LIM3; CPHD3; M2-LHX3 |
| NCBI Protein Information: | LIM/homeobox protein Lhx3 |
| UniProt Protein Name: | LIM/homeobox protein Lhx3 |
| Protein Family: | LIM/homeobox protein |
| UniProt Gene Name: | LHX3 |