Anti-LDHB Antibody (CAB7625)
- SKU:
- CAB7625
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-LDHB Antibody |
| 抗体コード: | CAB7625 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, A-431, Jurkat, A-549, Mouse brain, Mouse kidney, Mouse heart, Mouse lung, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human LDHB (NP_002291.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MATL KEKL IAPV AEEE ATVP NNKI TVVG VGQV GMAC AISI LGKS LADE LALV DVLE DKLK GEMM DLQH GSLF LQTP KIVA DKDY SVTA NSKI VVVT AGVR QQEG ESRL NLVQ RNVN VFKF IIPQ IVKY SPDC IIIV VSNP VDIL TYVT WKLS GLPK HRVI GSGC NLDS ARFR YLMA EKLG IHPS SCHG WILG EHGD SSVA VWSG VNVA GVSL QELN PEMG TDND SENW KEVH KMVV ESAY EVIK LKGY TNWA IGLS VADL IESM LKNL SRIH PVST MVKG MYGI ENEV FLSL PCIL NARG LTSV INQK LKDD EVAQ LKKS ADTL WDIQ KDLK DL |
| 遺伝子ID: | 3945 |
| Uniprot: | P07195 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 36kDa |
| 観察された分子量: | 37kDa |
| 同義語: | LDHB, HEL-S-281, LDH-B, LDH-H, LDHBD, TRG-5 |
| バックグラウンド: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. |
| NCBI Summary: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016] |
| UniProt Code: | P07195 |
| NCBI GenInfo Identifier: | 126041 |
| NCBI Gene ID: | 3945 |
| NCBI Accession: | P07195.2 |
| UniProt Related Accession: | P07195 |
| Molecular Weight: | ~ 37kDa |
| NCBI Full Name: | L-lactate dehydrogenase B chain |
| NCBI Synonym Full Names: | lactate dehydrogenase B |
| NCBI Official Symbol: | LDHB |
| NCBI Official Synonym Symbols: | LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281 |
| NCBI Protein Information: | L-lactate dehydrogenase B chain |
| UniProt Protein Name: | L-lactate dehydrogenase B chain |
| UniProt Synonym Protein Names: | LDH heart subunit; LDH-H; Renal carcinoma antigen NY-REN-46 |
| Protein Family: | L-lactate dehydrogenase |
| UniProt Gene Name: | LDHB |
| UniProt Entry Name: | LDHB_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LDHB antibody (CAB7625) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse stomach using LDHB antibody (CAB7625) at dilution of 1:100 (40x lens). |
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