Anti-L3MBTL2 Antibody (CAB10331)
- SKU:
- CAB10331
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-L3MBTL2 Antibody |
| 抗体コード: | CAB10331 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 486-705 of human L3MBTL2 (NP_113676.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, HL-60, HT-29 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 486-705 of human L3MBTL2 (NP_113676.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PATF CQKN DIEL TPPK GYEA QTFN WENY LEKT KSKA APSR LFNM DCPN HGFK VGMK LEAV DLME PRLI CVAT VKRV VHRL LSIH FDGW DSEY DQWV DCES PDIY PVGW CELT GYQL QPPV AAEP ATPL KAKE ATKK KKKQ FGKK RKRI PPTK TRPL RQGS KKPL LEDD PQGA RKIS SEPV PGEI IAVR VKEE HLDV ASPD KASS PELP VSVE NIKQ ETDD |
| 遺伝子ID: | 83746 |
| Uniprot: | Q969R5 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 69kDa/79kDa |
| 観察された分子量: | 95kDa |
| 同義語: | L3MBTL2, H-l(3)mbt-l, L3MBT |
| バックグラウンド: |
| UniProt Protein Function: | L3MBTL2: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Histone-binding Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: nucleoplasm; nucleus Molecular Function:histone binding; methylated histone residue binding; protein binding Biological Process: protein sumoylation |
| UniProt Code: | Q969R5 |
| NCBI GenInfo Identifier: | 27734418 |
| NCBI Gene ID: | 83746 |
| NCBI Accession: | Q969R5.1 |
| UniProt Secondary Accession: | Q969R5,Q8TEN1, Q96SC4, Q9BQI2, Q9UGS4, |
| UniProt Related Accession: | Q969R5 |
| Molecular Weight: | 79kDa |
| NCBI Full Name: | Lethal(3)malignant brain tumor-like protein 2 |
| NCBI Synonym Full Names: | L3MBTL2 polycomb repressive complex 1 subunit |
| NCBI Official Symbol: | L3MBTL2 |
| NCBI Official Synonym Symbols: | L3MBT; H-l(3)mbt-l |
| NCBI Protein Information: | lethal(3)malignant brain tumor-like protein 2 |
| UniProt Protein Name: | Lethal(3)malignant brain tumor-like protein 2 |
| Protein Family: | Lethal(3)malignant brain tumor-like protein |
| UniProt Gene Name: | L3MBTL2 |
 | Western blot analysis of extracts of various cell lines, using L3MBTL2 antibody (CAB10331) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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