Anti-IRX3 Antibody (CAB17765)
- SKU:
- CAB17765
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-IRX3 Antibody |
抗体コード: | CAB17765 |
抗体サイズ: | 20uL, 50 uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IRX3 (NP_077312.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IRX3 (NP_077312.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SNVL SSVY GAPY AAAA AAAA AQGY GAFL PYAA ELPI FPQL GAQY ELKD SPGV QHPA AAAA FPHP HPAF YPYG QYQF GDPS RPKN ATRE STST LKAW LNEH R |
遺伝子ID: | 79191 |
Uniprot: | P78415 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | IRX-1, IRXB1, IRX3 |
バックグラウンド: | IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009] |
UniProt Protein Function: | IRX3: Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells. Belongs to the TALE/IRO homeobox family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16q12.2 |
NCBI Summary: | IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009] |
UniProt Code: | P78415 |
NCBI GenInfo Identifier: | 47117874 |
NCBI Gene ID: | 79191 |
NCBI Accession: | P78415.3 |
UniProt Secondary Accession: | P78415,Q7Z4A4, Q7Z4A5, Q8IVC6, |
UniProt Related Accession: | P78415 |
Molecular Weight: | 52,119 Da |
NCBI Full Name: | Iroquois-class homeodomain protein IRX-3 |
NCBI Synonym Full Names: | iroquois homeobox 3 |
NCBI Official Symbol: | IRX3 |
NCBI Official Synonym Symbols: | IRX-1; IRXB1 |
NCBI Protein Information: | iroquois-class homeodomain protein IRX-3 |
UniProt Protein Name: | Iroquois-class homeodomain protein IRX-3 |
UniProt Synonym Protein Names: | Homeodomain protein IRXB1; Iroquois homeobox protein 3 |
Protein Family: | Iroquois-class homeodomain protein |
UniProt Gene Name: | IRX3 |
UniProt Entry Name: | IRX3_HUMAN |