Anti-IRF2BP1 Antibody (CAB4614)
- SKU:
- CAB4614
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IRF2BP1
Frequently bought together:
Description
| I抗体名: | IRF2BP1 Rabbit pAb |
| 抗体コード: | CAB4614 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | IRF2BP1 |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1). |
| 申し込み: | WB |
| 推奨される希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, HeLa, Jurkat, Mouse eye |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-240 of human IRF2BP1 (NP_056464.1). |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VLPE GRSP GPPA LKHP ATKD LAAA AAQG PQLP PPQA QPQP SGTG GGVS GQDR YDRA TSSG RLPL PSPA LEYT LGSR LANG LGRE EAVA EGAR RALL GSMP GLMP PGLL AAAV SGLG SRGL TLAP GLSP ARPL FGSD FEKE KQQR NADC LAEL NEAM RGRA EEWH GRPK AVRE QLLA LSAC A |
| 遺伝子ID: | 26145 |
| Uniprot: | Q8IU81 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 61kDa |
| 観察された分子量: | 62kDa |
| UniProt Protein Function: | IRF2BP1: Acts as a transcriptional corepressor in a IRF2- dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. Belongs to the IRF2BP family. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; EC 6.3.2.- Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: nucleoplasm; intracellular membrane-bound organelle Molecular Function:protein binding; metal ion binding; ligase activity Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Code: | Q8IU81 |
| NCBI GenInfo Identifier: | 74727955 |
| NCBI Gene ID: | 26145 |
| NCBI Accession: | Q8IU81.1 |
| UniProt Secondary Accession: | Q8IU81,Q53EL7, Q6DC95, Q9BRZ9, Q9Y4P4, |
| UniProt Related Accession: | Q8IU81 |
| Molecular Weight: | 584 |
| NCBI Full Name: | Interferon regulatory factor 2-binding protein 1 |
| NCBI Synonym Full Names: | interferon regulatory factor 2 binding protein 1 |
| NCBI Official Symbol: | IRF2BP1 |
| NCBI Protein Information: | interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; probable E3 ubiquitin-protein ligase IRF2BP1 |
| UniProt Protein Name: | Interferon regulatory factor 2-binding protein 1 |
| UniProt Synonym Protein Names: | Probable E3 ubiquitin-protein ligase IRF2BP1 (EC:6.3.2.-) |
| Protein Family: | Interferon regulatory factor 2-binding protein |
| UniProt Gene Name: | IRF2BP1 |
| UniProt Entry Name: | I2BP1_HUMAN |