Anti-IL36G Antibody (CAB8304)
- SKU:
- CAB8304
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | IL36G Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8304 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human IL36G (NP_062564.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human IL36G (NP_062564.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MRGT PGDA DGGG RAVY QSMC KPIT GTIN DLNQ QVWT LQGQ NLVA VPRS DSVT PVTV AVIT CKYP EALE QGRG DPIY LGIQ NPEM CLYC EKVG EQPT LQLK EQKI MDLY GQPE PVKP FLFY RAKT GRTS TLES VAFP DWFI ASSK RDQP IILT SELG KSYN TAFE LNIN D |
| 遺伝子ID: | 56300 |
| Uniprot: | Q9NZH8 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 14kDa/18kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | IL36G, IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1, IL1RP2 |
| バックグラウンド: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Il1f9: Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 2q12-q21 Cellular Component: extracellular space Molecular Function:interleukin-1 receptor binding; cytokine activity Biological Process: cell-cell signaling; cytokine and chemokine mediated signaling pathway; innate immune response; positive regulation of interleukin-6 production; negative regulation of myoblast differentiation; inflammatory response |
| NCBI Summary: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q9NZH8 |
| NCBI GenInfo Identifier: | 25008596 |
| NCBI Gene ID: | 56300 |
| NCBI Accession: | Q9NZH8.1 |
| UniProt Secondary Accession: | Q9NZH8,Q56B91, Q6UVX7, Q7RTZ9, |
| UniProt Related Accession: | Q9NZH8 |
| Molecular Weight: | 18,721 Da |
| NCBI Full Name: | Interleukin-36 gamma |
| NCBI Synonym Full Names: | interleukin 36, gamma |
| NCBI Official Symbol: | IL36G |
| NCBI Official Synonym Symbols: | IL1E; IL1F9; IL1H1; IL-1F9; IL-1H1; IL1RP2; IL-1RP2 |
| NCBI Protein Information: | interleukin-36 gamma; IL-1 epsilon; IL-1-epsilon; IL-1(EPSILON); interleukin-1 epsilon; IL-1 related protein 2; IL-1-related protein 2; interleukin-1 homolog 1; interleukin-1 family member 9; interleukin 1 family, member 9; interleukin 1-related protein 2 |
| UniProt Protein Name: | Interleukin-36 gamma |
| UniProt Synonym Protein Names: | IL-1-related protein 2; IL-1RP2; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 9; IL-1F9; Interleukin-1 homolog 1 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL36G |
| UniProt Entry Name: | IL36G_HUMAN |
 | Immunohistochemistry of paraffin-embedded rat lung using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human esophagus using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse lung using IL36G antibody (CAB8304) at dilution of 1:100 (40x lens). |
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