Anti-IFI27 Antibody (CAB14174)
- SKU:
- CAB14174
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| 抗体名: | Anti-IFI27 Antibody |
| 抗体コード: | CAB14174 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Rat |
| ポジティブサンプル: | Rat heart |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IFI27 (NP_005523.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEAS ALTS SAVT SVAK VVRV ASGS AVVL PLAR IATV VIGG VVAV PMVL SAMG FTAA GIAS SSIA AKMM SAAA IANG GGVA SGSL VATL QSLG ATGL SGLT |
| 遺伝子ID: | 3429 |
| Uniprot: | P40305 |
| セルラーロケーション: | Membrane, Mitochondrion, Multi-pass membrane protein |
| 計算された分子量: | 11kDa |
| 観察された分子量: | 11kDa |
| 同義語: | IFI27, FAM14D, ISG12, ISG12A, P27 |
| バックグラウンド: |
| UniProt Protein Function: | IFI27: Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. Belongs to the IFI6/IFI27 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 14q32 Cellular Component: integral to membrane; mitochondrial outer membrane; mitochondrion; nuclear inner membrane Molecular Function:lamin binding Biological Process: caspase activation; negative regulation of transcription from RNA polymerase II promoter; regulation of protein export from nucleus |
| UniProt Code: | P40305 |
| NCBI GenInfo Identifier: | 55925614 |
| NCBI Gene ID: | 3429 |
| NCBI Accession: | NP_005523.3 |
| UniProt Secondary Accession: | P40305,Q53YA6, Q6IEC1, Q96BK3, |
| UniProt Related Accession: | P40305 |
| Molecular Weight: | |
| NCBI Full Name: | interferon alpha-inducible protein 27, mitochondrial isoform 2 |
| NCBI Synonym Full Names: | interferon alpha inducible protein 27 |
| NCBI Official Symbol: | IFI27 |
| NCBI Official Synonym Symbols: | P27; ISG12; FAM14D; ISG12A |
| NCBI Protein Information: | interferon alpha-inducible protein 27, mitochondrial |
| UniProt Protein Name: | Interferon alpha-inducible protein 27, mitochondrial |
| UniProt Synonym Protein Names: | Interferon alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a) |
| Protein Family: | Interferon alpha-inducible protein |
| UniProt Gene Name: | IFI27 |
| UniProt Entry Name: | IFI27_HUMAN |
 | Western blot analysis of extracts of rat heart, using IFI27 antibody (CAB14174) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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