Anti-HSPA9 Antibody (CAB0558)
- SKU:
- CAB0558
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-HSPA9 Antibody |
| 抗体コード: | CAB0558 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-679 of human HSPA9 (NP_004125.3). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | MCF7, NIH/3T3, COS-7, Mouse brain, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-679 of human HSPA9 (NP_004125.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IGEV ILVG GMTR MPKV QQTV QDLF GRAP SKAV NPDE AVAI GAAI QGGV LAGD VTDV LLLD VTPL SLGI ETLG GVFT KLIN RNTT IPTK KSQV FSTA ADGQ TQVE IKVC QGER EMAG DNKL LGQF TLIG IPPA PRGV PQIE VTFD IDAN GIVH VSAK DKGT GREQ QIVI QSSG GLSK DDIE NMVK NAEK YAEE DRRK KERV EAVN MAEG IIHD TETK MEEF KDQL PADE CNKL KEEI SKMR ELLA RKDS ETGE NIRQ AASS LQQA SLKL FEMA YKKM ASER EGSG SSGT GEQK EDQK EEKQ |
| 遺伝子ID: | 3313 |
| Uniprot: | P38646 |
| セルラーロケーション: | Mitochondrion, Nucleus, nucleolus |
| 計算された分子量: | 73kDa |
| 観察された分子量: | 80kDa |
| 同義語: | HSPA9, CRP40, CSA, EVPLS, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74, SAAN, SIDBA4 |
| バックグラウンド: | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2. |
| UniProt Protein Function: | HSPA9B: Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone. Interacts with FXN. Interacts with HSCB. Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2. Belongs to the heat shock protein 70 family. |
| UniProt Protein Details: | Protein type:Nucleolus; Heat shock protein; Chaperone Chromosomal Location of Human Ortholog: 5q31.1 Cellular Component: focal adhesion; mitochondrion; cytoplasm; nucleolus Molecular Function:protein binding; ubiquitin protein ligase binding; unfolded protein binding; ATP binding Biological Process: cellular protein metabolic process; protein folding; protein export from nucleus; protein targeting to mitochondrion; negative regulation of apoptosis |
| NCBI Summary: | This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010] |
| UniProt Code: | P38646 |
| NCBI GenInfo Identifier: | 21264428 |
| NCBI Gene ID: | 3313 |
| NCBI Accession: | P38646.2 |
| UniProt Secondary Accession: | P38646,P30036, P31932, Q1HB43, Q53H23, Q6GU03, Q9BWB7 Q9UC56, B2RCM1, |
| UniProt Related Accession: | P38646 |
| Molecular Weight: | 679 |
| NCBI Full Name: | Stress-70 protein, mitochondrial |
| NCBI Synonym Full Names: | heat shock 70kDa protein 9 (mortalin) |
| NCBI Official Symbol: | HSPA9 |
| NCBI Official Synonym Symbols: | CSA; MOT; MOT2; CRP40; GRP75; PBP74; GRP-75; HSPA9B; MTHSP75; HEL-S-124m |
| NCBI Protein Information: | stress-70 protein, mitochondrial; mortalin-2; p66-mortalin; mortalin, perinuclear; heat shock 70kD protein 9B; peptide-binding protein 74; 75 kDa glucose-regulated protein; catecholamine-regulated protein 40; epididymis secretory sperm binding protein Li 124m |
| UniProt Protein Name: | Stress-70 protein, mitochondrial |
| UniProt Synonym Protein Names: | 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9; Mortalin; MOT; Peptide-binding protein 74; PBP74 |
| Protein Family: | Stress-70 protein |
| UniProt Gene Name: | HSPA9 |
| UniProt Entry Name: | GRP75_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HSPA9 antibody (CAB0558) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
 | Immunohistochemistry of paraffin-embedded rat kidney using HSPA9 antibody (CAB0558) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human lung cancer using HSPA9 antibody (CAB0558) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using HSPA9 antibody (CAB0558) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse heart using HSPA9 antibody (CAB0558) at dilution of 1:100 (40x lens). |
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