Anti-HGFAC Antibody (CAB10114)
- SKU:
- CAB10114
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-HGFAC Antibody |
| 抗体コード: | CAB10114 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 408-655 of human HGFAC (NP_001519.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | LO2, BT-474, SW620, Mouse liver, Mouse pancreas, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 408-655 of human HGFAC (NP_001519.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IIGG SSSL PGSH PWLA AIYI GDSF CAGS LVHT CWVV SAAH CFSH SPPR DSVS VVLG QHFF NRTT DVTQ TFGI EKYI PYTL YSVF NPSD HDLV LIRL KKKG DRCA TRSQ FVQP ICLP EPGS TFPA GHKC QIAG WGHL DENV SGYS SSLR EALV PLVA DHKC SSPE VYGA DISP NMLC AGYF DCKS DACQ GDSG GPLA CEKN GVAY LYGI ISWG DGCG RLHK PGVY TRVA NYVD WIND RIRP PRRL VAPS |
| 遺伝子ID: | 3083 |
| Uniprot: | Q04756 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 70kDa |
| 観察された分子量: | 75kDa |
| 同義語: | HGFAC, HGFA |
| バックグラウンド: | This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | HGFAC: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.4.21.-; Secreted; Protease Chromosomal Location of Human Ortholog: 4p16 Cellular Component: extracellular region; extracellular space Molecular Function:serine-type endopeptidase activity; serine-type peptidase activity Biological Process: proteolysis |
| NCBI Summary: | This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q04756 |
| NCBI GenInfo Identifier: | 547643 |
| NCBI Gene ID: | 3083 |
| NCBI Accession: | Q04756.1 |
| UniProt Secondary Accession: | Q04756,Q14726, Q2M1W7, Q53X47, |
| UniProt Related Accession: | Q04756 |
| Molecular Weight: | 70,682 Da |
| NCBI Full Name: | Hepatocyte growth factor activator |
| NCBI Synonym Full Names: | HGF activator |
| NCBI Official Symbol: | HGFAC |
| NCBI Official Synonym Symbols: | HGFA |
| NCBI Protein Information: | hepatocyte growth factor activator |
| UniProt Protein Name: | Hepatocyte growth factor activator |
| Protein Family: | Hepatocyte growth factor activator |
| UniProt Gene Name: | HGFAC |
| UniProt Entry Name: | HGFA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HGFAC antibody (CAB10114) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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