Anti-HAVCR1 Antibody (RACO0439)
- SKU:
- RACO0439
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 商品名: | HAVCR1 Antibody |
| Product SKU: | RACO0439 |
| サイズ: | 50ul |
| 宿主種: | Homo sapiens (Human) |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:5000 |
| 反応性: | Human, Mouse |
| 免疫原: | A synthesized peptide derived from human TIM 1 |
| 憲法: | Liquid |
| ストレージバッファ: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 精製方法: | Affinity-chromatography |
| 抗体のクローン性: | Monoclonal |
| アイソタイプ: | Rabbit IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4 (By similarity). May play a role in kidney injury and repair. |
| シノニム: | Hepatitis A virus cellular receptor 1 (HAVcr-1) (Kidney injury molecule 1) (KIM-1) (T-cell immunoglobulin and mucin domain-containing protein 1) (TIMD-1) (T-cell immunoglobulin mucin receptor 1) (TIM) (TIM-1) (T-cell membrane protein 1), HAVCR1, KIM1 TIM1 TIMD1 |
 | Western Blot. Positive WB detected in RAW264.7 whole cell lysate 293T whole cell lysate HepG2 whole cell lysate NIH/3T3 whole cell lysate All lanes TIM1 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 40 kDa. Observed band size: 50 kDa. |
| UniProt Protein Function: | TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 5q33.2 Cellular Component: integral to membrane Molecular Function:viral receptor activity Biological Process: entry of virus into host cell Disease: Ige Responsiveness, Atopic |
| NCBI Summary: | The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q96D42 |
| NCBI GenInfo Identifier: | 73919877 |
| NCBI Gene ID: | 26762 |
| NCBI Accession: | Q96D42.2 |
| UniProt Secondary Accession: | Q96D42,O43656, |
| UniProt Related Accession: | Q96D42 |
| Molecular Weight: | 364 |
| NCBI Full Name: | Hepatitis A virus cellular receptor 1 |
| NCBI Synonym Full Names: | hepatitis A virus cellular receptor 1 |
| NCBI Official Symbol: | HAVCR1 |
| NCBI Official Synonym Symbols: | TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1 |
| NCBI Protein Information: | hepatitis A virus cellular receptor 1; kidney injury molecule 1; T-cell membrane protein 1; T-cell immunoglobulin mucin receptor 1; T-cell immunoglobulin mucin family member 1; T cell immunoglobin domain and mucin domain protein 1 |
| UniProt Protein Name: | Hepatitis A virus cellular receptor 1 |
| UniProt Synonym Protein Names: | Kidney injury molecule 1; KIM-1; T-cell immunoglobulin and mucin domain-containing protein 1; TIMD-1; T-cell immunoglobulin mucin receptor 1; TIM; TIM-1; T-cell membrane protein 1 |
| UniProt Gene Name: | HAVCR1 |
| UniProt Entry Name: | HAVR1_HUMAN |