Anti-GTF3A Antibody (CAB8426)
- SKU:
- CAB8426
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-GTF3A Antibody |
抗体コード: | CAB8426 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GTF3A (NP_002088.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | SW480 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GTF3A (NP_002088.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDPP AVVA ESVS SLTI ADAF IAAG ESSA PTPP RPAL PRRF ICSF PDCS ANYS KAWK LDAH LCKH TGER PFVC DYEG CGKA FIRD YHLS RHIL THTG EKPF |
遺伝子ID: | 2971 |
Uniprot: | Q92664 |
セルラーロケーション: | Nucleus |
計算された分子量: | 38kDa/41kDa |
観察された分子量: | 38kDa |
同義語: | GTF3A, AP2, TFIIIA |
バックグラウンド: | The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. |
UniProt Protein Function: | GTF3A: Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription initiation complex; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 13q12.3-q13.1 Cellular Component: nucleoplasm; nucleus Biological Process: rRNA transcription; transcription from RNA polymerase III promoter |
NCBI Summary: | The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q92664 |
NCBI GenInfo Identifier: | 172045838 |
NCBI Gene ID: | 2971 |
NCBI Accession: | Q92664.3 |
UniProt Secondary Accession: | Q92664,Q12963, Q13097, B7ZBK5, |
UniProt Related Accession: | Q92664 |
Molecular Weight: | 38,779 Da |
NCBI Full Name: | Transcription factor IIIA |
NCBI Synonym Full Names: | general transcription factor IIIA |
NCBI Official Symbol: | GTF3A |
NCBI Official Synonym Symbols: | AP2; TFIIIA |
NCBI Protein Information: | transcription factor IIIA |
UniProt Protein Name: | Transcription factor IIIA |
UniProt Gene Name: | GTF3A |
UniProt Entry Name: | TF3A_HUMAN |
View AllClose