Anti-GSDMD Antibody (CAB18281)
- SKU:
- CAB18281
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
| 抗体名: | Anti-GSDMD Antibody |
| 抗体コード: | CAB18281 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF IP |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human GSDMD. |
| 申し込み: | WB IHC IF IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | PC-3, THP-1, Jurkat, Rat spleen |
| 免疫原: | Recombinant protein of human GSDMD. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 79792 |
| Uniprot: | P57764 |
| セルラーロケーション: | |
| 計算された分子量: | 53kDa |
| 観察された分子量: | 53KDa/23KDa |
 | Western blot - GSDMD Rabbit pAb (CAB18281) |
| 同義語: | DF5L, DFNA5L, FKSG10, GSDMDC1, GSDMD |
| バックグラウンド: | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. |
| UniProt Protein Function: | FKSG10: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytosol; extracellular region; extracellular space; ficolin-1-rich granule lumen; NLRP3 inflammasome complex; nucleoplasm; plasma membrane; tertiary granule lumen Molecular Function:cardiolipin binding; phosphatidic acid binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylserine binding; protein binding Biological Process: cellular response to extracellular stimulus; cytolysis; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; inflammatory response; innate immune response; neutrophil degranulation; pore complex assembly; positive regulation of interleukin-1 beta secretion; protein homooligomerization; pyroptosis |
| NCBI Summary: | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| UniProt Code: | P57764 |
| NCBI GenInfo Identifier: | 261878494 |
| NCBI Gene ID: | 79792 |
| NCBI Accession: | NP_001159709.1 |
| UniProt Secondary Accession: | P57764,Q96Q98, A8K702, D3DWJ9, |
| UniProt Related Accession: | P57764 |
| Molecular Weight: | 52,801 Da |
| NCBI Full Name: | gasdermin-D |
| NCBI Synonym Full Names: | gasdermin D |
| NCBI Official Symbol: | GSDMD |
| NCBI Official Synonym Symbols: | DF5L; DFNA5L; FKSG10; GSDMDC1 |
| NCBI Protein Information: | gasdermin-D |
| UniProt Protein Name: | Gasdermin-D |
| UniProt Synonym Protein Names: | Gasdermin domain-containing protein 1 |
| Protein Family: | Gasdermin |
| UniProt Gene Name: | GSDMD |