Anti-GPRC5A Antibody (CAB8173)
- SKU:
- CAB8173
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | GPRC5A Rabbit Polyclonal Antibody |
| 抗体コード: | CAB8173 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-357 of human GPRC5A (NP_003970.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Mouse lung, Mouse kidney, Mouse stomach |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-357 of human GPRC5A (NP_003970.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LAYV SPEF WLLT KQRN PMDY PVED AFCK PQLV KKSY GVEN RAYS QEEI TQGF EETG DTLY APYS THFQ LQNQ PPQK EFSI PRAH AWPS PYKD YEVK KEGS |
| 遺伝子ID: | 9052 |
| Uniprot: | Q8NFJ5 |
| セルラーロケーション: | Cell membrane, Cytoplasmic vesicle membrane, Multi-pass membrane protein |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 41kDa |
| 同義語: | GPRC5A, GPCR5A, PEIG-1, RAI3, RAIG1, TIG1 |
| バックグラウンド: | This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. |
| UniProt Protein Function: | RAIG1: a G protein coupled receptor that is induced by all-trans retinoic acid (ATRA). Retinoic acids (RA) are a group of pleiotropic signaling molecules that regulate a broad range of physiologic and developmental processes. RAIG1 is expressed in lung tissue and in several lung cancer cell lines. This retinoic acid-inducible GPCR provides evidence for an interaction between retinoid and G-protein signaling pathways. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 3; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 12p13.1 Cellular Component: cytoplasmic vesicle membrane; integral to plasma membrane; intracellular membrane-bound organelle; plasma membrane Molecular Function:G-protein coupled receptor activity; protein binding Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of epidermal growth factor receptor activity; signal transduction |
| NCBI Summary: | This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8NFJ5 |
| NCBI GenInfo Identifier: | 46396943 |
| NCBI Gene ID: | 9052 |
| NCBI Accession: | Q8NFJ5.2 |
| UniProt Secondary Accession: | Q8NFJ5,O95357, B3KV45, |
| UniProt Related Accession: | Q8NFJ5 |
| Molecular Weight: | 40,251 Da |
| NCBI Full Name: | Retinoic acid-induced protein 3 |
| NCBI Synonym Full Names: | G protein-coupled receptor class C group 5 member A |
| NCBI Official Symbol: | GPRC5A |
| NCBI Official Synonym Symbols: | RAI3; TIG1; RAIG1; GPCR5A; PEIG-1 |
| NCBI Protein Information: | retinoic acid-induced protein 3 |
| UniProt Protein Name: | Retinoic acid-induced protein 3 |
| UniProt Synonym Protein Names: | G-protein coupled receptor family C group 5 member A; Phorbol ester induced gene 1 |
| Protein Family: | Retinoic acid-induced protein |
| UniProt Gene Name: | GPRC5A |
| UniProt Entry Name: | RAI3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GPRC5A antibody (CAB8173) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunohistochemistry of paraffin-embedded human stomach using GPRC5A antibody (CAB8173) at dilution of 1:100 (40x lens). |
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