Anti-GIGYF2 Antibody (CAB12069)
- SKU:
- CAB12069
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GIGYF2 Antibody |
| 抗体コード: | CAB12069 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:100 |
| 反応性: | Human, Rat |
| ポジティブサンプル: | 293T, HeLa, U-87MG?Jurkat, Raji, LO2 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | VDEG EECS DSEG SHNE EAKE PDKT NKKE GEKT DRVG VASE ETPQ TSSS SARP GTPS DHQS QEAS QFER KDEP KTEQ TEKA EEET RMEN SLPA KVPS RGDE MVAD VQQP LSQI PSDT ASPL LILP PPVP NPSP TLRP VETP VVGA PGMG SVS |
| 遺伝子ID: | 26058 |
| Uniprot: | Q6Y7W6 |
| セルラーロケーション: | |
| 計算された分子量: | 148kDa/149kDa/150kDa/152kDa |
| 観察された分子量: | 190kDa |
| 同義語: | GIGYF2, GYF2, PARK11, PERQ2, PERQ3, TNRC15 |
| バックグラウンド: | This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors. |
| NCBI Summary: | This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
| UniProt Code: | Q6Y7W6 |
| NCBI GenInfo Identifier: | 74710467 |
| NCBI Gene ID: | 26058 |
| NCBI Accession: | Q6Y7W6.1 |
| UniProt Secondary Accession: | Q6Y7W6,O75137, Q7Z2Z8, Q7Z3I2, Q96HU4, Q9NV82, A6H8W4 B9EG55, E9PBB0, |
| UniProt Related Accession: | Q6Y7W6 |
| Molecular Weight: | 149,486 Da |
| NCBI Full Name: | PERQ amino acid-rich with GYF domain-containing protein 2 |
| NCBI Synonym Full Names: | GRB10 interacting GYF protein 2 |
| NCBI Official Symbol: | GIGYF2 |
| NCBI Official Synonym Symbols: | GYF2; PERQ2; PERQ3; PARK11; TNRC15 |
| NCBI Protein Information: | PERQ amino acid-rich with GYF domain-containing protein 2 |
| UniProt Protein Name: | PERQ amino acid-rich with GYF domain-containing protein 2 |
| UniProt Synonym Protein Names: | GRB10-interacting GYF protein 2; Trinucleotide repeat-containing gene 15 protein |
| Protein Family: | PERQ amino acid-rich with GYF domain-containing protein |
| UniProt Gene Name: | GIGYF2 |
| UniProt Entry Name: | PERQ2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GIGYF2 antibody (CAB12069) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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