Anti-GGH Antibody (CAB5464)
- SKU:
- CAB5464
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GGH Antibody |
| 抗体コード: | CAB5464 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, Mouse kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-230 of human GGH (NP_003869.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RPHG DTAK KPII GILM QKCR NKVM KNYG RYYI AASY VKYL ESAG ARVV PVRL DLTE KDYE ILFK SING ILFP GGSV DLRR SDYA KVAK IFYN LSIQ SFDD GDYF PVWG TCLG FEEL SLLI SGEC LLTA TDTV DVAM PLNF TGGQ LHSR MFQN FPTE LLLS LAVE PLTA NFHK WSLS VKNF TMNE KLKK FFNV LTTN TDGK IEFI ST |
| 遺伝子ID: | 8836 |
| Uniprot: | Q92820 |
| セルラーロケーション: | Lysosome, Melanosome, Secreted, extracellular space |
| 計算された分子量: | 35kDa |
| 観察された分子量: | 32kDa |
| 同義語: | GGH, GH |
| バックグラウンド: | This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. |
| UniProt Protein Function: | GGH: Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Belongs to the peptidase C26 family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Cofactor and Vitamin Metabolism - folate biosynthesis; Secreted; Protease; EC 3.4.19.9 Chromosomal Location of Human Ortholog: 8q12.3 Cellular Component: extracellular space; nucleus; vacuole Molecular Function:exopeptidase activity; omega peptidase activity Biological Process: tetrahydrofolylpolyglutamate metabolic process |
| NCBI Summary: | This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92820 |
| NCBI GenInfo Identifier: | 6016127 |
| NCBI Gene ID: | 8836 |
| NCBI Accession: | Q92820.2 |
| UniProt Related Accession: | Q92820 |
| Molecular Weight: | 35,964 Da |
| NCBI Full Name: | Gamma-glutamyl hydrolase |
| NCBI Synonym Full Names: | gamma-glutamyl hydrolase |
| NCBI Official Symbol: | GGH |
| NCBI Official Synonym Symbols: | GH |
| NCBI Protein Information: | gamma-glutamyl hydrolase |
| UniProt Protein Name: | Gamma-glutamyl hydrolase |
| UniProt Synonym Protein Names: | Conjugase; GH; Gamma-Glu-X carboxypeptidase |
| Protein Family: | Gamma-glutamyl hydrolase |
| UniProt Gene Name: | GGH |
| UniProt Entry Name: | GGH_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GGH antibody (CAB5464) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of A-549 cells using GGH antibody (CAB5464). |
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