Anti-GFAP Antibody (CAB19058)
- SKU:
- CAB19058
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-GFAP Antibody |
| 抗体コード: | CAB19058 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human GFAP |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain, U-251MG |
| 免疫原: | A synthesized peptide derived from human GFAP |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2670 |
| Uniprot: | P14136 |
| セルラーロケーション: | |
| 計算された分子量: | 50kDa |
| 観察された分子量: | 48kDa |
 | Western blot - GFAP Rabbit mAb (CAB19058) |
| 同義語: | ALXDRD, GFAP |
| バックグラウンド: | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| UniProt Protein Function: | GFAP: a class-III intermediate filament protein. A cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. An additional transcript variant isoform has been described, but its full length sequence has not been determined. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 17q21 Cellular Component: membrane; cytoplasm; intermediate filament; cytosol Molecular Function:integrin binding; structural constituent of cytoskeleton; kinase binding Biological Process: Bergmann glial cell differentiation; extracellular matrix organization and biogenesis; regulation of neurotransmitter uptake; response to wounding; intermediate filament organization; neurite regeneration; astrocyte development Disease: Alexander Disease |
| NCBI Summary: | This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
| UniProt Code: | P14136 |
| NCBI GenInfo Identifier: | 121135 |
| NCBI Gene ID: | 2670 |
| NCBI Accession: | P14136.1 |
| UniProt Secondary Accession: | P14136,Q53H98, Q5D055, Q6ZQS3, Q7Z5J6, Q7Z5J7, Q96KS4 Q96P18, Q9UFD0, B2RD44, D3DX59, E9PAX3, |
| UniProt Related Accession: | P14136 |
| Molecular Weight: | 432 |
| NCBI Full Name: | Glial fibrillary acidic protein |
| NCBI Synonym Full Names: | glial fibrillary acidic protein |
| NCBI Official Symbol: | GFAP |
| NCBI Protein Information: | glial fibrillary acidic protein |
| UniProt Protein Name: | Glial fibrillary acidic protein |
| Protein Family: | Glial fibrillary acidic protein |
| UniProt Gene Name: | GFAP |
| UniProt Entry Name: | GFAP_HUMAN |