Anti-FTSJ1 Antibody (CAB7967)
- SKU:
- CAB7967
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | FTSJ1 Rabbit Polyclonal Antibody |
| 抗体コード: | CAB7967 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-329 of human FTSJ1 (NP_036412.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HT-1080 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 170-329 of human FTSJ1 (NP_036412.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LQVF FSSV LCAK PRSS RNSS IEAF AVCQ GYDP PEGF IPDL SKPL LDHS YDPD FNQL DGPT RIIV PFVT CGDL SSYD SDRS YPLD LEGG SEYK YTPP TQPP ISPP YQEA CTLK RKGQ LAKE IRPQ DCPI SRVD TFPQ PLAA PQCH TLLA PEME DNEM SCSP |
| 遺伝子ID: | 24140 |
| Uniprot: | Q9UET6 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 35kDa/36kDa |
| 観察された分子量: | 26kDa |
| 同義語: | FTSJ1, CDLIV, JM23, MRX44, MRX9, SPB1, TRMT7 |
| バックグラウンド: | This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | FTSJ1: Defects in FTSJ1 are the cause of mental retardation X- linked type 44 (MRX44). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the methyltransferase superfamily. RlmE family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.1.1.205; Methyltransferase Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytoplasm Molecular Function:tRNA methyltransferase activity Biological Process: tRNA methylation Disease: Mental Retardation, X-linked 9 |
| NCBI Summary: | This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q9UET6 |
| NCBI GenInfo Identifier: | 12643879 |
| NCBI Gene ID: | 24140 |
| NCBI Accession: | Q9UET6.2 |
| UniProt Secondary Accession: | Q9UET6,O75670, B2RCJ0, |
| UniProt Related Accession: | Q9UET6 |
| Molecular Weight: | 35,867 Da |
| NCBI Full Name: | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
| NCBI Synonym Full Names: | FtsJ RNA methyltransferase homolog 1 (E. coli) |
| NCBI Official Symbol: | FTSJ1 |
| NCBI Official Synonym Symbols: | JM23; MRX9; SPB1; CDLIV; MRX44; TRMT7 |
| NCBI Protein Information: | putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
| UniProt Protein Name: | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
| UniProt Synonym Protein Names: | 2'-O-ribose RNA methyltransferase TRM7 homolog |
| UniProt Gene Name: | FTSJ1 |
| UniProt Entry Name: | TRM7_HUMAN |
 | Western blot analysis of extracts of HT-1080 cells, using FTSJ1 Antibody (CAB7967) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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