Anti-FIBP Antibody (CAB19908)[KO Validated]

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SKU:
CAB19908
Product type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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Description

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抗体名:Anti-FIBP Antibody [KO Validated]
抗体コード:CAB19908
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Rat
宿主種:Rabbit
免疫原:Recombinant protein of human FIBP.
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Rat
ポジティブサンプル:HeLa
免疫原:Recombinant protein of human FIBP.
精製方法:Affinity purification
ストレージバッファ:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:Email for sequence
遺伝子ID:9158
Uniprot:O43427
セルラーロケーション:Endomembrane system, Nucleus, Peripheral membrane protein
計算された分子量:41kDa
観察された分子量:43KDa
Anti-FIBP Antibody [KO Validated] (CAB19908)Western blot analysis of extracts from normal (control) and FIBP knockout (KO) HeLa cells, using FIBP antibody (CAB19908) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
同義語:FIBP, FGFIBP, FIBP-1, TROFAS
バックグラウンド:Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: nucleoplasm; membrane; mitochondrion; endomembrane system; nucleus

Molecular Function:fibroblast growth factor binding

Biological Process: fibroblast growth factor receptor signaling pathway

NCBI Summary:Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O43427
NCBI GenInfo Identifier:13431517
NCBI Gene ID:9158
NCBI Accession:O43427.3
UniProt Secondary Accession:O43427,Q27Q85, Q6IBQ3, Q9HD65, A8K0J7,
UniProt Related Accession:O43427
Molecular Weight:364
NCBI Full Name:Acidic fibroblast growth factor intracellular-binding protein
NCBI Synonym Full Names:fibroblast growth factor (acidic) intracellular binding protein
NCBI Official Symbol:FIBP  
NCBI Official Synonym Symbols:FGFIBP; FIBP-1  
NCBI Protein Information:acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein
UniProt Protein Name:Acidic fibroblast growth factor intracellular-binding protein
UniProt Synonym Protein Names:FGF-1 intracellular-binding protein
Protein Family:Acidic fibroblast growth factor intracellular-binding protein
UniProt Gene Name:FIBP  
UniProt Entry Name:FIBP_HUMAN
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