Anti-FERMT2 Antibody (CAB8709)
- SKU:
- CAB8709
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-FERMT2 Antibody |
| 抗体コード: | CAB8709 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, HT-29, LO2, MCF7, HT-1080, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 380-550 of human FERMT2 (NP_006823.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | KVFK PKKL TLKG YKQY WCTF KDTS ISCY KSKE ESSG TPAH QMNL RGCE VTPD VNIS GQKF NIKL LIPV AEGM NEIW LRCD NEKQ YAHW MAAC RLAS KGKT MADS SYNL EVQN ILSF LKMQ HLNP DPQL IPEQ ITTD ITPE CLVS PRYL KKYK NKQI TARI LEAH QNVA QMS |
| 遺伝子ID: | 10979 |
| Uniprot: | Q96AC1 |
| セルラーロケーション: | Cell junction, Cell projection, Cell surface, Cytoplasm, Cytoplasmic side, I band, Membrane, Nucleus, Peripheral membrane protein, cell cortex, cytoskeleton, focal adhesion, lamellipodium membrane, myofibril, sarcomere |
| 計算された分子量: | 72kDa/77kDa/78kDa |
| 観察された分子量: | 78kDa |
| 同義語: | FERMT2, KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2 |
| バックグラウンド: |
| UniProt Protein Function: | kindlin-2: Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Belongs to the kindlin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 14q22.1 Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; focal adhesion; nucleoplasm; nucleus Molecular Function:phosphatidylinositol-3,4,5-triphosphate binding; protein binding Biological Process: cell-matrix adhesion; focal adhesion formation; integrin activation; integrin-mediated signaling pathway; transforming growth factor beta receptor signaling pathway; Wnt receptor signaling pathway |
| UniProt Code: | Q96AC1 |
| NCBI GenInfo Identifier: | 38258220 |
| NCBI Gene ID: | 10979 |
| NCBI Accession: | Q96AC1.1 |
| UniProt Secondary Accession: | Q96AC1,Q14840, Q86TY7, B5TJY2, |
| UniProt Related Accession: | Q96AC1 |
| Molecular Weight: | 78,675 Da |
| NCBI Full Name: | Fermitin family homolog 2 |
| NCBI Synonym Full Names: | fermitin family member 2 |
| NCBI Official Symbol: | FERMT2 |
| NCBI Official Synonym Symbols: | MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B |
| NCBI Protein Information: | fermitin family homolog 2 |
| UniProt Protein Name: | Fermitin family homolog 2 |
| UniProt Synonym Protein Names: | Kindlin-2; Mitogen-inducible gene 2 protein; MIG-2; Pleckstrin homology domain-containing family C member 1; PH domain-containing family C member 1 |
| Protein Family: | Fermitin family |
| UniProt Gene Name: | FERMT2 |
| UniProt Entry Name: | FERM2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FERMT2 antibody (CAB8709) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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