Anti-ESD Antibody (CAB6228)

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SKU:
CAB6228
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-ESD Antibody
抗体コード:CAB6228
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB IHC
反応性:Human, Mouse
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1).
申し込み:WB IHC
推奨希釈:WB 1:500 - 1:2000 IHC 1:50 - 1:200
反応性:Human, Mouse
ポジティブサンプル:MCF7, Jurkat, HepG2, 293T, Mouse kidney
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MALK QISS NKCF GGLQ KVFE HDSV ELNC KMKF AVYL PPKA ETGK CPAL YWLS GLTC TEQN FISK SGYH QSAS EHGL VVIA PDTS PRGC NIKG EDES WDFG TGAG FYVD ATED PWKT NYRM YSYV TEEL PQLI NANF PVDP QRMS IFGH SMGG HGAL ICAL KNPG KYKS VSAF APIC NPVL CPWG KKAF SGYL GTDQ SKWK AYDA THLV KSYP GSQL DILI DQGK DDQF LLDG QLLP DNFI AACT EKKI PVVF RLQE GYDH SYYF IATF ITDH IRHH AKYL NA
遺伝子ID:2098
Uniprot:P10768
セルラーロケーション:Cytoplasm, Cytoplasmic vesicle
計算された分子量:31kDa
観察された分子量:36kDa
同義語:ESD, FGH
バックグラウンド:This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease.
UniProt Protein Function:esterase D: an enzyme that catalyzes the conversion of carboxylic esters and H2O into alcohol and a carboxylic anion.
UniProt Protein Details:

Protein type:EC 3.1.2.12; EC 3.1.1.56; Hydrolase

Chromosomal Location of Human Ortholog: 13q14.1-q14.2

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; cytoplasmic membrane-bound vesicle; plasma membrane

Molecular Function:S-formylglutathione hydrolase activity; methylumbelliferyl-acetate deacetylase activity; hydrolase activity, acting on ester bonds

Biological Process: formaldehyde catabolic process

NCBI Summary:This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq, Feb 2009]
UniProt Code:P10768
NCBI GenInfo Identifier:544254
NCBI Gene ID:2098
NCBI Accession:P10768.2
UniProt Secondary Accession:P10768,Q5TBU8, Q5TBV0, Q5TBV2, Q9BVJ2,
UniProt Related Accession:P10768
Molecular Weight:282
NCBI Full Name:S-formylglutathione hydrolase
NCBI Synonym Full Names:esterase D
NCBI Official Symbol:ESD  
NCBI Official Synonym Symbols:FGH  
NCBI Protein Information:S-formylglutathione hydrolase; esterase 10; esterase D/formylglutathione hydrolase; methylumbelliferyl-acetate deacetylase
UniProt Protein Name:S-formylglutathione hydrolase
UniProt Synonym Protein Names:Esterase D; Methylumbelliferyl-acetate deacetylase (EC:3.1.1.56)
UniProt Gene Name:ESD  
UniProt Entry Name:ESTD_HUMAN
Anti-ESD Antibody (CAB6228)Western blot analysis of extracts of various cell lines, using ESD antibody (CAB6228) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-ESD Antibody (CAB6228)Immunohistochemistry of paraffin-embedded Human trachea using ESD antibody (CAB6228) at dilution of 1:100 (40x lens).
Anti-ESD Antibody (CAB6228)Immunohistochemistry of paraffin-embedded mouse lung using ESD antibody (CAB6228) at dilution of 1:100 (40x lens).
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