Anti-EPB41L1 Antibody (CAB18361)
- SKU:
- CAB18361
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-EPB41L1 Antibody |
| 抗体コード: | CAB18361 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human EPB41L1. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: |
| 免疫原: | Recombinant protein of human EPB41L1. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 2036 |
| Uniprot: | Q9H4G0 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | Refer to figures |
| 同義語: | 4.1N, MRD11, EPB41L1 |
| バックグラウンド: |
| UniProt Protein Function: | EPB41L1: May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases. Defects in EPB41L1 are the cause of mental retardation autosomal dominant type 11 (MRD11). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 20q11.2-q12 Cellular Component: cytoskeleton; extrinsic to membrane; plasma membrane; cytosol Molecular Function:actin binding; structural molecule activity Biological Process: synaptic transmission; cortical actin cytoskeleton organization and biogenesis Disease: Mental Retardation, Autosomal Dominant 11 |
| NCBI Summary: | Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| UniProt Code: | Q9H4G0 |
| NCBI GenInfo Identifier: | 14916561 |
| NCBI Gene ID: | 2036 |
| NCBI Accession: | Q9H4G0.2 |
| UniProt Secondary Accession: | Q9H4G0,O15046, Q4VXM6, Q4VXM7, Q4VXM8, Q4VXN4, Q6ZT61 Q8IUU7, Q96CV5, Q96L65, |
| UniProt Related Accession: | Q9H4G0 |
| Molecular Weight: | 78,831 Da |
| NCBI Full Name: | Band 4.1-like protein 1 |
| NCBI Synonym Full Names: | erythrocyte membrane protein band 4.1-like 1 |
| NCBI Official Symbol: | EPB41L1 |
| NCBI Official Synonym Symbols: | 4.1N; MRD11 |
| NCBI Protein Information: | band 4.1-like protein 1; neuronal protein 4.1; neuron-type nonerythroid protein 4.1 |
| UniProt Protein Name: | Band 4.1-like protein 1 |
| UniProt Synonym Protein Names: | Neuronal protein 4.1; 4.1N |
| Protein Family: | Band 4.1-like protein |
| UniProt Gene Name: | EPB41L1 |
| UniProt Entry Name: | E41L1_HUMAN |