Anti-Enpp1 Antibody (CAB17876)
- SKU:
- CAB17876
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-Enpp1 Antibody |
| 抗体コード: | CAB17876 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 580-730 of mouse Enpp1 (NP_032839.3). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, 293T, Mouse kidney, Mouse liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 580-730 of mouse Enpp1 (NP_032839.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PIYN PSHP KEEG FLSQ CPIK STSN DLGC TCDP WIVP IKDF EKQL NLTT EDDD IYHM TVPY GRPR ILLK QHRV CLLQ QQQF LTGY SLDL LMPL WASY TFLS NDQF SRDD FSNC LYQD LRIP LSPV HKCS YYKS NSKL SYGF LTPP RLNR VSN |
| 遺伝子ID: | 18605 |
| Uniprot: | G3X9S2 |
| セルラーロケーション: | |
| 計算された分子量: | 103kDa |
| 観察された分子量: | 120kDa/170kDa |
 | Western blot - Enpp1 Rabbit pAb (CAB17876) |
| 同義語: | Pca, ttw, twy, M6S1, NPP1, Npps, PC-1, Ly-41, Pca-1, Pdnp1, C76301, CD203c, E-NPP1, E-NPP 1, AI428932, 4833416E15Rik, Enpp1 |
| バックグラウンド: | This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms. |