Anti-DTNB Antibody (CAB12866)
- SKU:
- CAB12866
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DTNB Antibody |
| 抗体コード: | CAB12866 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 381-560 of human DTNB (NP_899205.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 381-560 of human DTNB (NP_899205.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RLAA EAGN VTRP PTDL SFNF DANK QQRQ LIAE LENK NREI LQEI QRLR LEHE QASQ PTPE KAQQ NPTL LAEL RLLR QRKD ELEQ RMSA LQES RREL MVQL EELM KLLK AQAT GSPH TSPT HGGG RPMP MPVR STSA GSTP THCP QDSL SGVG GDVQ EAFA QAEE GAEE EEEK MQNG KDRG |
| 遺伝子ID: | 1838 |
| Uniprot: | O60941 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 61kDa/63kDa/64kDa/68kDa/69kDa/71kDa |
| 観察された分子量: | 60kDa |
| 同義語: | DTNB |
| バックグラウンド: | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. |
| UniProt Protein Function: | DTNB: dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Calcium-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p24 Cellular Component: cytoplasm; synapse Molecular Function:zinc ion binding |
| NCBI Summary: | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60941 |
| NCBI GenInfo Identifier: | 13626370 |
| NCBI Gene ID: | 1838 |
| NCBI Accession: | O60941.1 |
| UniProt Secondary Accession: | O60941,O43782, O60881, O75538, Q86VR4, Q96AW0, Q9UE14 Q9UE15, Q9UE16, B7Z733, F5GZG4, G5E9F6, |
| UniProt Related Accession: | O60941 |
| Molecular Weight: | 69,294 Da |
| NCBI Full Name: | Dystrobrevin beta |
| NCBI Synonym Full Names: | dystrobrevin, beta |
| NCBI Official Symbol: | DTNB |
| NCBI Protein Information: | dystrobrevin beta; DTN-B; beta-dystrobrevin |
| UniProt Protein Name: | Dystrobrevin beta |
| UniProt Synonym Protein Names: | Beta-dystrobrevin |
| Protein Family: | Dystrobrevin |
| UniProt Gene Name: | DTNB |
| UniProt Entry Name: | DTNB_HUMAN |
 | Western blot analysis of extracts of mouse brain, using DTNB antibody (CAB12866) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
View AllClose