Anti-DPF2 Antibody (CAB13271)
- SKU:
- CAB13271
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | Anti-DPF2 Antibody |
| 抗体コード: | CAB13271 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-391 of human DPF2 (NP_006259.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa, NIH/3T3, Mouse brain, Rat pancreas |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 126-391 of human DPF2 (NP_006259.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DPLE KRGA PDPR VDDD SLGE FPVT NSRA RKRI LEPD DFLD DLDD EDYE EDTP KRRG KGKS KGKG VGSA RKKL DASI LEDR DKPY ACDI CGKR YKNR PGLS YHYA HSHL AEEE GEDK EDSQ PPTP VSQR SEEQ KSKK GPDG LALP NNYC DFCL GDSK INKK TGQP EELV SCSD CGRS GHPS CLQF TPVM MAAV KTYR WQCI ECKC CNIC GTSE NDDQ LLFC DDCD RGYH MYCL TPSM SEPP EGSW SCHL CLDL LKEK ASIY QNQN SS |
| 遺伝子ID: | 5977 |
| Uniprot: | Q92785 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 23kDa/44kDa |
| 観察された分子量: | 50kDa |
| 同義語: | DPF2, REQ, UBID4, ubi-d4 |
| バックグラウンド: | The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. |
| UniProt Protein Function: | requiem: May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells. Belongs to the requiem/DPF family. |
| UniProt Protein Details: | Protein type:Apoptosis; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 11q13 Cellular Component: centrosome; cytoplasm; intracellular membrane-bound organelle; nuclear chromatin; nucleoplasm Molecular Function:protein binding; zinc ion binding Biological Process: apoptosis; regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| NCBI Summary: | The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92785 |
| NCBI GenInfo Identifier: | 2842711 |
| NCBI Gene ID: | 5977 |
| NCBI Accession: | Q92785.2 |
| UniProt Secondary Accession: | Q92785,A8K7C9, B4DT58, |
| UniProt Related Accession: | Q92785 |
| Molecular Weight: | 23,599 Da |
| NCBI Full Name: | Zinc finger protein ubi-d4 |
| NCBI Synonym Full Names: | double PHD fingers 2 |
| NCBI Official Symbol: | DPF2 |
| NCBI Official Synonym Symbols: | REQ; UBID4; ubi-d4 |
| NCBI Protein Information: | zinc finger protein ubi-d4 |
| UniProt Protein Name: | Zinc finger protein ubi-d4 |
| UniProt Synonym Protein Names: | Apoptosis response zinc finger protein; BRG1-associated factor 45D; BAF45D; D4, zinc and double PHD fingers family 2; Protein requiem |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | DPF2 |
| UniProt Entry Name: | REQU_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DPF2 antibody (CAB13271) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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