Anti-DGKB Antibody (CAB16364)
- SKU:
- CAB16364
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-DGKB Antibody |
| 抗体コード: | CAB16364 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 544-773 of human DGKB (NP_663733.1). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 544-773 of human DGKB (NP_663733.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LMKI LKDI ENST EIML DRWK FEVI PNDK DEKG DPVP YSII NNYF SIGV DASI AHRF HIMR EKHP EKFN SRMK NKFW YFEF GTSE TFSA TCKK LHES VEIE CDGV QIDL INIS LEGI AILN IPSM HGGS NLWG ESKK RRSH RRIE KKGS DKRT TVTD AKEL KFAS QDLS DQLL EVVG LEGA MEMG QIYT GLKS AGRR LAQC SCVV IRTS KSLP MQID GEPW MQTP CTVS TE |
| 遺伝子ID: | 1607 |
| Uniprot: | Q9Y6T7 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 87kDa/90kDa |
| 観察された分子量: |
| 同義語: | DGKB, DAGK2, DGK, DGK-BETA |
| バックグラウンド: | Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | DGKB: is a cytoplasmic enzyme that phosphorylates 1,2-diacylglycerol. A regulator of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). |
| UniProt Protein Details: | Protein type:EC 2.7.1.107; Kinase, lipid; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 7p21.2 Cellular Component: plasma membrane Molecular Function:diacylglycerol kinase activity Biological Process: glycerolipid metabolic process; lipid phosphorylation; platelet activation |
| NCBI Summary: | Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017] |
| UniProt Code: | Q9Y6T7 |
| NCBI GenInfo Identifier: | 12643960 |
| NCBI Gene ID: | 1607 |
| NCBI Accession: | Q9Y6T7.2 |
| UniProt Secondary Accession: | Q9Y6T7,O75241, Q2M377, Q75MF9, Q75MU7, Q86UI5, Q86UM9 Q9UQ29, A4D116, A4D117, A8MXU2, |
| UniProt Related Accession: | Q9Y6T7 |
| Molecular Weight: | 91kDa |
| NCBI Full Name: | Diacylglycerol kinase beta |
| NCBI Synonym Full Names: | diacylglycerol kinase beta |
| NCBI Official Symbol: | DGKB |
| NCBI Official Synonym Symbols: | DGK; DAGK2; DGK-BETA |
| NCBI Protein Information: | diacylglycerol kinase beta |
| UniProt Protein Name: | Diacylglycerol kinase beta |
| UniProt Synonym Protein Names: | 90 kDa diacylglycerol kinase; Diglyceride kinase beta; DGK-beta |
| Protein Family: | Diacylglycerol kinase |
| UniProt Gene Name: | DGKB |
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