UniProt Protein Function: | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. |
UniProt Code: | Q9NUI1 |
NCBI GenInfo Identifier: | 10190704 |
NCBI Gene ID: | 26063 |
NCBI Accession: | NP_065715.1 |
UniProt Secondary Accession: | Q9NUI1,Q6ZRS7, Q96ET0, |
UniProt Related Accession: | Q9NUI1 |
Molecular Weight: | 30 kDa |
NCBI Full Name: | peroxisomal 2,4-dienoyl-CoA reductase |
NCBI Synonym Full Names: | 2,4-dienoyl-CoA reductase 2 |
NCBI Official Symbol: | DECR2 |
NCBI Official Synonym Symbols: | PDCR; SDR17C1 |
NCBI Protein Information: | peroxisomal 2,4-dienoyl-CoA reductase |
UniProt Protein Name: | Peroxisomal 2,4-dienoyl-CoA reductase |
UniProt Synonym Protein Names: | 2,4-dienoyl-CoA reductase 2; Short chain dehydrogenase/reductase family 17C member 1 |
UniProt Gene Name: | DECR2 |