Anti-CXCL14 Antibody (CAB9857)
- SKU:
- CAB9857
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-CXCL14 Antibody |
抗体コード: | CAB9857 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-111 of human CXCL14 (NP_004878.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | NCI-H460 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-111 of human CXCL14 (NP_004878.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SKCK CSRK GPKI RYSD VKKL EMKP KYPH CEEK MVII TTKS VSRY RGQE HCLH PKLQ STKR FIKW YNAW NEKR RVYE E |
遺伝子ID: | 9547 |
Uniprot: | O95715 |
セルラーロケーション: | Secreted |
計算された分子量: | 13kDa |
観察された分子量: | 13kDa |
同義語: | CXCL14, BMAC, BRAK, KEC, KS1, MIP-2g, MIP2G, NJAC, SCYB14 |
バックグラウンド: | This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. |
UniProt Protein Function: | CXCL14: Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. Belongs to the intercrine alpha (chemokine CxC) family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Chemokine; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q31 Cellular Component: Golgi apparatus; extracellular space Molecular Function:chemokine activity Biological Process: cell-cell signaling; immune response; negative regulation of myoblast differentiation; chemotaxis; signal transduction; inner ear development |
NCBI Summary: | This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014] |
UniProt Code: | O95715 |
NCBI GenInfo Identifier: | 292495003 |
NCBI Gene ID: | 9547 |
NCBI Accession: | O95715.2 |
UniProt Secondary Accession: | O95715,Q6UW97, Q86U69, Q9BTR1, Q9NS21, B3KQU8, |
UniProt Related Accession: | O95715 |
Molecular Weight: | 13,078 Da |
NCBI Full Name: | C-X-C motif chemokine 14 |
NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 14 |
NCBI Official Symbol: | CXCL14 |
NCBI Official Synonym Symbols: | KEC; KS1; BMAC; BRAK; NJAC; MIP2G; MIP-2g; SCYB14 |
NCBI Protein Information: | C-X-C motif chemokine 14; bolekine; MIP-2 gamma; chemokine BRAK; breast and kidney; tumor-suppressing chemokine; small-inducible cytokine B14; CXC chemokine in breast and kidney; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK) |
UniProt Protein Name: | C-X-C motif chemokine 14 |
UniProt Synonym Protein Names: | Chemokine BRAK; MIP-2G; Small-inducible cytokine B14 |
UniProt Gene Name: | CXCL14 |
UniProt Entry Name: | CXL14_HUMAN |
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